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英文名称 中文名称 CAS
Mortality; Evaluation of median lethal concentration (LC50). 死亡率;半数致死浓度(LC50)评价。
Median lethal concentration 半数致死浓度
Genetic engineering animal model 遗传工程动物模型
Genetically modified animal model 遗传修饰动物模型
Should we experiment with animals 应该用动物做实验吗
Animal experiment of depression 抑郁动物实验
Animal model of depression 抑郁动物模型
Factors affecting animal models 影响动物模型的因素
Why do experiments with animals 用动物做实验的原因
Carry out appropriate toxicity tests with experimental animals 用实验动物进行适当的毒性试验
Comet experiment; Genotoxicity evaluation. 慧星实验;基因毒性评价。
Genotoxicity 基因毒性
The incidence of renal capsule edema;. 肾包膜水肿发生率;。
Cardiovascular toxicity heart rate; Heart rhythm; The incidence of pericardial edema; Incidence of bleeding; Incidence of changes in blood flow velocity; Incidence of thrombosis 心血管毒性心率;心律;心包水肿发生率;出血发生率;血流速度变化的发生率;血栓发生率
Fluorescence signal intensity of apoptotic cells (AO staining, TUNEL staining) 凋亡细胞荧光信号强度(AO染色、TUNEL染色)
Fluorescence signal intensity of apoptotic cells in central nervous system; 中枢神经凋亡细胞荧光信号强度;
Incidence of developmental toxicity and teratogenicity (brain, jaw, eye, kidney, intestine, trunk / tail / spinal cord / somite, body coloring, circulatory system, body edema, bleeding) 发育毒性与致畸性(脑、下颚、眼、肾脏、肠道、躯干/尾/脊髓/体节、身体着色、循环系统、身体水肿、出血)毒性发生率
Vitellogenin (VTG) content detection; The expression of genes related to hypothalamic pituitary gonadal axis was detected. 卵黄蛋白原(VTG)含量检测;下丘脑-垂体-性腺 轴线相关基因表达量检测。
Peripheral motor nerve length; Incidence of brain degeneration; 周围运动神经长度;脑变性发生率;
Number of hematotoxic neutrophils; Number of macrophages; Number of red blood cells (signal intensity); Blood flow. 血液毒性中性粒细胞数量;巨噬细胞数量;红细胞数量(信号强度);血流量。
Degree of liver degeneration; Yolk sac size. 肝变性程度;卵黄囊大小。
Reproductive toxicity and reproductive ability evaluation; Gonadal growth evaluation; Histological sections of gonads; 生殖毒性生殖能力评价;性腺生长评价;性腺病理组织切片;
apoptotic cell 凋亡细胞
Incidence of acute toxicity (brain, jaw, eye, kidney, intestine, trunk / tail / spinal cord / somite, body coloring, circulatory system, body edema, bleeding) 急性毒性(脑、下颚、眼、肾脏、肠道、躯干/尾/脊髓/体节、身体着色、循环系统、身体水肿、出血)毒性发生率
Anaphylactic reaction 类过敏反应
inflammatory reaction 炎症反应
Number of neutrophils; Expression level of inflammatory factors. 中性粒细胞数量;炎症因子表达水平。
Ocular toxicity 眼毒性
Eye size; Ocular apoptotic cells; Ocular vascular area; Ocular histopathology. 眼睛大小;眼部凋亡细胞;眼部血管面积;眼组织病理学。
Gastrointestinal toxicity 胃肠道毒性
Tryptase expression level (OD value); Anaphylactic reaction test. Tryptase表达水平(OD值);类过敏反应检测。
Intestinal morphology; Intestinal peristalsis requires motor function. 肠道形态学;肠蠕需动功能。
Skin toxicity 皮肤毒性
Phenotypic observation 表型观察
Nephrotoxicity 肾毒性
Audiotoxicity 听毒性
Fluorescence signal intensity of hair cells 毛细胞荧光信号强度
Bone mineral density (fluorescence signal intensity); Number of vertebrae. 骨密度(荧光信号强度);脊椎骨数量。
Behavior (touch response, movement influence, light and dark influence); 行为学(触碰反应、运动影响、光暗影响);
Hepatotoxicity (juvenile fish) 肝毒性(幼鱼)
Gastrointestinal peristalsis function (autonomic nerve). 胃肠蠕动功能(植物神经)。
Behavior 行为学
Immunotoxicity 免疫毒性
Skin irritation; Muscle texture; Quantification of skin apoptotic cells; Skin pigment changes. 皮肤刺激;肌肉纹理;皮肤凋亡细胞定量;皮肤色素变化。
Carcinogenicity (mice) 致癌性(小鼠)
Macrophage function 巨噬细胞功能
Osteotoxicity 骨毒性
Behavioral toxicity 行为毒性
neurotoxicity 神经毒性
Platelet aggregation thrombosis model 血小板聚集性血栓模型
Protective model of vascular endothelial injury 血管内皮损伤保护模型
Myocardial injury protective agent screening model 心肌损伤保护剂筛选模型
Spleen yang deficiency model 脾阳虚模型
Oxygen free radical (ROS) scavenger screening model 氧自由基(ROs)清除剂筛选模型
Induced qi stagnation and blood stasis thrombosis model 诱导气滞血瘀型血栓模型
PM2. 5. Screening model of drainage promoters PM2.5促排剂筛选模型
Mitochondrial function 线粒体功能
Intestinal mucus secretion function 肠道粘液分泌功能
Induction model of high sugar and high fat diet 高糖高脂饮食诱导模型
Hypolipidemic model 降血脂模型
Pharmacodynamic evaluation model of slimming drugs 减肥药药效评价模型
Screening model of gastrointestinal motility inhibitors 胃肠动力抑制剂筛选模型
Uric acid model 尿酸模型
Fat metabolism model 脂肪代谢模型
Screening model of energy metabolism regulator 能量代谢调节剂筛选模型
Screening model of antialcoholic agents 解酒剂筛选模型
Screening model of P-glycoprotein inhibitors P-糖蛋白抑制剂筛选模型
Metabolic system 代谢系统
Induction model of caspase activity 对Caspase活性的诱导作用模型
Efficacy evaluation model of drug efficacy evaluation system 药物功效评价 系统 功效评价模型
Anti angiogenesis model 抗血管形成模型
Apoptosis inhibitor screening model 凋亡抑制剂筛选模型
Angiogenesis inhibitor screening 血管形成抑制剂筛选
Safety evaluation 安全性评价
Preclinical drug experiment preclinical research (outsourcing entrusted experiment) 药物临床前实验 临床前研究(外包委托实验)
Drug evaluation and testing items (outsourcing entrusted experiment) 药物评价检测项目(外包委托实验)
Preclinical spinal cord injury experiment 临床前脊髓损伤实验
Preclinical evaluation of reproductive toxicity 生殖毒临床前评价
Preclinical evaluation of antiviral research and development 抗病毒研发临床前评价
Preclinical evaluation of cardiac drugs 心脏药物临床前评价
mycoalert mycoplasma detection kit 支原体检测试剂盒
Intestinal digestive function 肠道消化功能
Screening model of angiogenesis promoters 血管再生促进剂筛选模型
Erythrocyte thrombosis model 红细胞性血栓模型
Cardio cerebrovascular 心脑血管
Mouse bradycardia model 小鼠心动过缓模型
Drug screening model for the treatment of heart failure 心衰治疗药物筛选模型
Screening model of renal protective agents 肾功能保护剂筛选模型
Screening model of hepatoprotective drugs 保肝药筛选模型
Liver kidney model 肝肾模型
Cytochrome P450 analysis 细胞色素P450分析
Screening model of bone development promoters 骨骼发育促进剂筛选模型
Skeletal muscle 骨骼肌肉
Drug safety evaluation model index 药物安全性评价 评价模型 指标
Cartilage injury model 软骨损伤模型
Analgesic drug screening 镇痛药物筛选
Promoting tissue regeneration / wound healing 促组织再生作用/伤口愈合
Screening model of therapeutic agents for osteoporosis 骨质疏松症治疗剂筛选模型
Embryotoxicity (OECD standard) 胚胎毒性(OECD标准)
The incidence of egg coagulation; No heart rate; Hatching rate; The incidence of no somite formation; Incidence of tail non separation; 卵凝结发生率;无心跳发生率;孵化率;体节未形成发生率;尾部未分离发生率;
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