英文名称 |
中文名称 |
CAS |
Metabolic system
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代谢系统 |
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Screening model of gastrointestinal motility inhibitors
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胃肠动力抑制剂筛选模型 |
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Myocardial injury protective agent screening model
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心肌损伤保护剂筛选模型 |
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Screening model of renal protective agents
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肾功能保护剂筛选模型 |
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Reproductive toxicity and reproductive ability evaluation; Gonadal growth evaluation; Histological sections of gonads;
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生殖毒性生殖能力评价;性腺生长评价;性腺病理组织切片; |
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Gastrointestinal peristalsis function (autonomic nerve).
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胃肠蠕动功能(植物神经)。 |
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inflammatory reaction
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炎症反应 |
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Intestinal morphology; Intestinal peristalsis requires motor function.
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肠道形态学;肠蠕需动功能。 |
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Carry out appropriate toxicity tests with experimental animals
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用实验动物进行适当的毒性试验 |
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Genetically modified animal model
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遗传修饰动物模型 |
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Apoptosis inhibitor screening model
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凋亡抑制剂筛选模型 |
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Fat metabolism model
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脂肪代谢模型 |
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Erythrocyte thrombosis model
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红细胞性血栓模型 |
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Mouse bradycardia model
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小鼠心动过缓模型 |
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Incidence of developmental toxicity and teratogenicity (brain, jaw, eye, kidney, intestine, trunk / tail / spinal cord / somite, body coloring, circulatory system, body edema, bleeding)
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发育毒性与致畸性(脑、下颚、眼、肾脏、肠道、躯干/尾/脊髓/体节、身体着色、循环系统、身体水肿、出血)毒性发生率 |
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Behavior (touch response, movement influence, light and dark influence);
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行为学(触碰反应、运动影响、光暗影响); |
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Behavior
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行为学 |
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Anaphylactic reaction
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类过敏反应 |
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Animal model of depression
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抑郁动物模型 |
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neurotoxicity
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神经毒性 |
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Immunotoxicity
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免疫毒性 |
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Preclinical drug experiment preclinical research (outsourcing entrusted experiment)
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药物临床前实验 临床前研究(外包委托实验) |
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Efficacy evaluation model of drug efficacy evaluation system
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药物功效评价 系统 功效评价模型 |
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Mitochondrial function
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线粒体功能 |
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Protective model of vascular endothelial injury
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血管内皮损伤保护模型 |
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Promoting tissue regeneration / wound healing
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促组织再生作用/伤口愈合 |
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Embryotoxicity (OECD standard)
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胚胎毒性(OECD标准) |
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Degree of liver degeneration; Yolk sac size.
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肝变性程度;卵黄囊大小。 |
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Osteotoxicity
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骨毒性 |
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Phenotypic observation
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表型观察 |
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Induction model of high sugar and high fat diet
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高糖高脂饮食诱导模型 |
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Screening model of antialcoholic agents
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解酒剂筛选模型 |
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Screening model of angiogenesis promoters
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血管再生促进剂筛选模型 |
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Cytochrome P450 analysis
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细胞色素P450分析 |
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Cartilage injury model
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软骨损伤模型 |
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apoptotic cell
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凋亡细胞 |
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The incidence of renal capsule edema;.
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肾包膜水肿发生率;。 |
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Ocular toxicity
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眼毒性 |
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Mortality; Evaluation of median lethal concentration (LC50).
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死亡率;半数致死浓度(LC50)评价。 |
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Screening model of P-glycoprotein inhibitors
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P-糖蛋白抑制剂筛选模型 |
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Screening model of energy metabolism regulator
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能量代谢调节剂筛选模型 |
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Induced qi stagnation and blood stasis thrombosis model
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诱导气滞血瘀型血栓模型 |
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Liver kidney model
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肝肾模型 |
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Cardiovascular toxicity heart rate; Heart rhythm; The incidence of pericardial edema; Incidence of bleeding; Incidence of changes in blood flow velocity; Incidence of thrombosis
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心血管毒性心率;心律;心包水肿发生率;出血发生率;血流速度变化的发生率;血栓发生率 |
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Fluorescence signal intensity of apoptotic cells in central nervous system;
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中枢神经凋亡细胞荧光信号强度; |
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Carcinogenicity (mice)
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致癌性(小鼠) |
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Tryptase expression level (OD value); Anaphylactic reaction test.
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Tryptase表达水平(OD值);类过敏反应检测。 |
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Animal experiment of depression
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抑郁动物实验 |
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Preclinical evaluation of cardiac drugs
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心脏药物临床前评价 |
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Anti angiogenesis model
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抗血管形成模型 |
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Cardio cerebrovascular
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心脑血管 |
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PM2. 5. Screening model of drainage promoters
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PM2.5促排剂筛选模型 |
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Screening model of bone development promoters
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骨骼发育促进剂筛选模型 |
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The incidence of egg coagulation; No heart rate; Hatching rate; The incidence of no somite formation; Incidence of tail non separation;
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卵凝结发生率;无心跳发生率;孵化率;体节未形成发生率;尾部未分离发生率; |
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Nephrotoxicity
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肾毒性 |
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Bone mineral density (fluorescence signal intensity); Number of vertebrae.
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骨密度(荧光信号强度);脊椎骨数量。 |
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Median lethal concentration
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半数致死浓度 |
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Should we experiment with animals
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应该用动物做实验吗 |
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Skin irritation; Muscle texture; Quantification of skin apoptotic cells; Skin pigment changes.
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皮肤刺激;肌肉纹理;皮肤凋亡细胞定量;皮肤色素变化。 |
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Safety evaluation
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安全性评价 |
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Preclinical evaluation of antiviral research and development
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抗病毒研发临床前评价 |
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Uric acid model
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尿酸模型 |
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Intestinal digestive function
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肠道消化功能 |
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Skeletal muscle
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骨骼肌肉 |
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Screening model of therapeutic agents for osteoporosis
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骨质疏松症治疗剂筛选模型 |
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Fluorescence signal intensity of apoptotic cells (AO staining, TUNEL staining)
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凋亡细胞荧光信号强度(AO染色、TUNEL染色) |
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Audiotoxicity
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听毒性 |
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Eye size; Ocular apoptotic cells; Ocular vascular area; Ocular histopathology.
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眼睛大小;眼部凋亡细胞;眼部血管面积;眼组织病理学。 |
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Genotoxicity
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基因毒性 |
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Induction model of caspase activity
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对Caspase活性的诱导作用模型 |
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Pharmacodynamic evaluation model of slimming drugs
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减肥药药效评价模型 |
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Drug screening model for the treatment of heart failure
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心衰治疗药物筛选模型 |
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Screening model of hepatoprotective drugs
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保肝药筛选模型 |
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Number of hematotoxic neutrophils; Number of macrophages; Number of red blood cells (signal intensity); Blood flow.
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血液毒性中性粒细胞数量;巨噬细胞数量;红细胞数量(信号强度);血流量。 |
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Peripheral motor nerve length; Incidence of brain degeneration;
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周围运动神经长度;脑变性发生率; |
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Macrophage function
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巨噬细胞功能 |
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Gastrointestinal toxicity
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胃肠道毒性 |
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Why do experiments with animals
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用动物做实验的原因 |
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Genetic engineering animal model
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遗传工程动物模型 |
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mycoalert mycoplasma detection kit
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支原体检测试剂盒 |
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Preclinical spinal cord injury experiment
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临床前脊髓损伤实验 |
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Angiogenesis inhibitor screening
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血管形成抑制剂筛选 |
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Hypolipidemic model
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降血脂模型 |
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Platelet aggregation thrombosis model
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血小板聚集性血栓模型 |
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Oxygen free radical (ROS) scavenger screening model
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氧自由基(ROs)清除剂筛选模型 |
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Incidence of acute toxicity (brain, jaw, eye, kidney, intestine, trunk / tail / spinal cord / somite, body coloring, circulatory system, body edema, bleeding)
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急性毒性(脑、下颚、眼、肾脏、肠道、躯干/尾/脊髓/体节、身体着色、循环系统、身体水肿、出血)毒性发生率 |
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Vitellogenin (VTG) content detection; The expression of genes related to hypothalamic pituitary gonadal axis was detected.
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卵黄蛋白原(VTG)含量检测;下丘脑-垂体-性腺 轴线相关基因表达量检测。 |
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Behavioral toxicity
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行为毒性 |
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Number of neutrophils; Expression level of inflammatory factors.
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中性粒细胞数量;炎症因子表达水平。 |
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Factors affecting animal models
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影响动物模型的因素 |
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Drug evaluation and testing items (outsourcing entrusted experiment)
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药物评价检测项目(外包委托实验) |
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Preclinical evaluation of reproductive toxicity
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生殖毒临床前评价 |
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Spleen yang deficiency model
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脾阳虚模型 |
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Intestinal mucus secretion function
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肠道粘液分泌功能 |
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Analgesic drug screening
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镇痛药物筛选 |
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Drug safety evaluation model index
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药物安全性评价 评价模型 指标 |
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Hepatotoxicity (juvenile fish)
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肝毒性(幼鱼) |
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Fluorescence signal intensity of hair cells
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毛细胞荧光信号强度 |
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Skin toxicity
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皮肤毒性 |
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Comet experiment; Genotoxicity evaluation.
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慧星实验;基因毒性评价。 |
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