Supplier Product Identification Physical and Chemical Properties First Aid Measures Handling and Storage Hazards Identification Exposure Controls/Personal Protection Fire Fighting Measures Accidental Release Measures Stability and Reactivity
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Diflunisal(22494-42-4)

Supplier Product Identification Physical and Chemical Properties First Aid Measures Handling and Storage Hazards Identification Exposure Controls/Personal Protection Fire Fighting Measures Accidental Release Measures Stability and Reactivity

Product Identification

Product Name
Diflunisal
Synonyms
5-(2,4-Difluorophenyl)-2-hydroxybenzoic acid
5-(2,4-Difluorophenyl)salicylic acid
Fluodonil
CAS
22494-42-4
Formula
C13H8F2O3
Molecular Weight
250.2
EINECS
245-034-9
RTECS
DV2030000
RTECS Class
Drug; Mutagen; Reproductive Effector; Human Data
Merck
12,3190
Beilstein/Gmelin
2654431
Beilstein Reference
6-10

Physical and Chemical Properties

Solubility in water
Slightly soluble
Melting Point
210 - 211
Boiling Point
390
Vapor Pressure
1E-6 (25 C)
pKa/pKb
2.94 (pKa)
Partition Coefficient
4.24
Heat Of Vaporization
67.1 kJ/mol
Usage
Antiinflammatory drug.

First Aid Measures

Ingestion
If swallowed, wash out mouth with water provided person is conscious. Call a physician.
Inhalation
If inhaled, remove to fresh air. If breathing becomes difficult, call a physician.
Skin
In case of skin contact, flush with copious amounts of water for at least 15 minutes. Remove contaminated clothing and shoes. Call a physician.
Eyes
In case of contact with eyes, flush with copious amounts of water for at least 15 minutes. Assure adequate flushing by separating the eyelids with fingers. Call a physician.

Handling and Storage

Storage
Keep tightly closed. Store in a cool dry place.

Hazards Identification

Inhalation
May be harmful if inhaled. Material is irritating to mucous membranes and upper respiratory tract.
Skin
May be harmful if absorbed through the skin.
Ingestion
Harmful if swallowed.
Hazards
Emits toxic fumes under fire conditions.
EC Risk Phrase
22 36/37/38 63
EC Safety Phrase
22 26 36

Exposure Controls/Personal Protection

Personal Protection
Wear appropriate government approved respirator, chemical-resistant gloves, safety goggles, other protective clothing.
Exposure Effects
Harmful if swallowed. Irritating to eyes, respiratory system and skin. Possible risk of harm to the unborn child. Possible sensitizer. Target organ(s): Blood. Liver.

Fire Fighting Measures

Flash Point
188
Fire Fighting
Extinguish using Carbon dioxide, dry chemical powder, or appropriate foam. Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.

Accidental Release Measures

Small spills/leaks
Sweep up, place in a bag and hold for waste disposal. Avoid raising dust. Ventilate area and wash spill site after material pickup is complete.

Stability and Reactivity

Stability
Stable at normal temperatures and pressures.
Decomposition
Carbon monoxide, Carbon dioxide, Hydrogen fluoride.
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