Supplier Product Identification Physical and Chemical Properties First Aid Measures Handling and Storage Hazards Identification Exposure Controls/Personal Protection Fire Fighting Measures Accidental Release Measures Stability and Reactivity
Home > 17-(Cyclopropylmethyl)-4,5-epoxy-3,14-dihydroxymorphinan-6-one > 17-(Cyclopropylmethyl)-4,5-epoxy-3,14-dihydroxymorphinan-6-one(16590-41-3)

17-(Cyclopropylmethyl)-4,5-epoxy-3,14-dihydroxymorphinan-6-one(16590-41-3)

Supplier Product Identification Physical and Chemical Properties First Aid Measures Handling and Storage Hazards Identification Exposure Controls/Personal Protection Fire Fighting Measures Accidental Release Measures Stability and Reactivity

Product Identification

Product Name
17-(Cyclopropylmethyl)-4,5-epoxy-3,14-dihydroxymorphinan-6-one
Synonyms
17-(Cyclopropylmethyl)-4,5-epoxy-3,14-dihydroxymorphinan-6-one
Celupan
n-Cyclopropylmethyl-14-hydroxydihydromorphinone
Trexan
Um-792
CAS
16590-41-3
Formula
C20H23NO4
Molecular Weight
341.41
EINECS
240-649-9
RTECS
QD2155000
RTECS Class
Drug; Mutagen; Reproductive Effector; Human Data
Merck
12,6450
Beilstein/Gmelin
3596648

Physical and Chemical Properties

Appearance
Crystals from acetone.
Solubility in water
2038 mg/L
Melting Point
168-170
Vapor Pressure
2.0e-16
Partition Coefficient
.534
Usage
Medication.

First Aid Measures

Ingestion
Seek medical attention. If individual is drowsy or unconscious, do not give anything by mouth; place individual on the left side with the head down. Contact a physician, medical facility, or poison control center for advice about whether to induce vomiting. If possible, do not leave individual unattended.
Inhalation
If symptoms develop, move individual away from exposure and into fresh air. If symptoms persist, seek medical attention. If breathing is difficult, administer oxygen. Keep person warm and quiet; seek immediate medical attention.
Skin
Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes.
Eyes
If symptoms develop, immediately move individual away from exposure and into fresh air. Flush eyes gently with water for at least 15 minutes while holding eyelids apart; seek immediate medical attention.

Handling and Storage

Storage
Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.
Handling
All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.

Hazards Identification

Inhalation
Respiratory failure occurred in animal studies following acute toxic doses. Pulmonary edema may result from abrupt reversal of opioid effects.
Ingestion
Nausea, vomiting, diarrhea, dry mouth and dyspepsia may occur following therapeutic or overdoses.

Exposure Controls/Personal Protection

Personal Protection
Chemical splash goggles in compliance with OSHA regulations are advised; however, OSHA regulations also permit other type safety glasses. Whre chemical resistant gloves. To prevent repeated or prolonged skin contact, wear impervious clothing and boots.
Respirators
Use NIOSH/MSHA approved respirator appropriate for exposure of concern.
Exposure Effects
Blood pressure may be increased (more probable) or decreased in the event of an overdose. Increased pulse rate may occur. Fever may occur. seizures resulting in death occurred in acute toxicity studies in animals. More common adverse effects of these agents include tremors, insomnia, dizziness, nervousness and anxiety.

Fire Fighting Measures

Fire Fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Use agent most appropriate to extinguish fire.

Accidental Release Measures

Small spills/leaks
Evacuate area and ventilate. Wear protective equipment. If required, use an inert absrobent. Sweep up and place in an appropriate container for disposal. Wash contaminated surfaces.

Stability and Reactivity

Stability
No data.
Incompatibilities
Strong oxidizing agents.
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