Home > 7-Chloro-5-(2-chlorophenyl)-1,3-dihydro-3-hydroxy-2H-1,4-benzodiazepin-2-one > 7-Chloro-5-(2-chlorophenyl)-1,3-dihydro-3-hydroxy-2H-1,4-benzodiazepin-2-one(846-49-1)
7-Chloro-5-(2-chlorophenyl)-1,3-dihydro-3-hydroxy-2H-1,4-benzodiazepin-2-one(846-49-1)
Product Identification
Physical and Chemical Properties
First Aid Measures
Handling and Storage
Hazards Identification
Exposure Controls/Personal Protection
Fire Fighting Measures
Stability and Reactivity
Product Identification
Product Name
7-Chloro-5-(2-chlorophenyl)-1,3-dihydro-3-hydroxy-2H-1,4-benzodiazepin-2-one
7-Chloro-5-(2-chlorophenyl)-1,3-dihydro-3-hydroxy-2H-1,4-benzodiazepin-2-one
Synonyms
7-Chloro-5-(2-chlorophenyl)-1,3-dihydro-3-hydroxy-2H-1,4-benzodiazepin-2-one
Delormetazepam
Demethyllormetazepam
o-Chloroxazepam
7-Chloro-5-(2-chlorophenyl)-1,3-dihydro-3-hydroxy-2H-1,4-benzodiazepin-2-one
Delormetazepam
Demethyllormetazepam
o-Chloroxazepam
CAS
846-49-1
846-49-1
Formula
C15H10Cl2N2O2
C15H10Cl2N2O2
Molecular Weight
321.16000000000003
321.16000000000003
EINECS
212-687-6
212-687-6
RTECS
DF0350000
DF0350000
RTECS Class
Drug; Reproductive Effector; Human Data
Drug; Reproductive Effector; Human Data
Merck
12,5609
12,5609
Beilstein/Gmelin
759084
759084
Beilstein Reference
5-25-02-00248
5-25-02-00248
Physical and Chemical Properties
Solubility in water
Insoluble
Insoluble
Melting Point
166 - 168
166 - 168
Boiling Point
534
534
Vapor Pressure
3E-12 (25 C)
3E-12 (25 C)
pKa/pKb
10.78 (pKa)
10.78 (pKa)
Heat Of Vaporization
85.3 kJ/mol
85.3 kJ/mol
Usage
Anxiolytic.
Anxiolytic.
First Aid Measures
Ingestion
If swallowed, wash out mouth with water provided person is conscious. Call a physician immediately.
If swallowed, wash out mouth with water provided person is conscious. Call a physician immediately.
Inhalation
If inhaled, remove to fresh air. If not breathing give artificial respiration. If breathing is difficult, give oxygen.
If inhaled, remove to fresh air. If not breathing give artificial respiration. If breathing is difficult, give oxygen.
Skin
In case of skin contact, flush with copious amounts of water for at least 15 minutes. Remove contaminated clothing and shoes. Call a physician.
In case of skin contact, flush with copious amounts of water for at least 15 minutes. Remove contaminated clothing and shoes. Call a physician.
Eyes
In case of contact with eyes, flush with copious amounts of water for at least 15 minutes. Assure adequate flushing by separating the eyelids with fingers. Call a physician.
In case of contact with eyes, flush with copious amounts of water for at least 15 minutes. Assure adequate flushing by separating the eyelids with fingers. Call a physician.
Handling and Storage
Storage
Keep tightly closed.
Keep tightly closed.
Hazards Identification
Inhalation
May be harmful if inhaled. Material may be irritating to mucous membranes and upper respiratory tract.
May be harmful if inhaled. Material may be irritating to mucous membranes and upper respiratory tract.
Skin
May cause skin irritation. May be harmful if absorbed through the skin.
May cause skin irritation. May be harmful if absorbed through the skin.
Eyes
May cause eye irritation.
May cause eye irritation.
Ingestion
Harmful if swallowed.
Harmful if swallowed.
Hazards
Emits toxic fumes under fire conditions.
Emits toxic fumes under fire conditions.
EC Risk Phrase
63
63
EC Safety Phrase
36/37
36/37
Exposure Controls/Personal Protection
Personal Protection
Compatible chemical-resistant gloves. Chemical safety goggles.
Compatible chemical-resistant gloves. Chemical safety goggles.
Respirators
Government approved respirator.
Government approved respirator.
Exposure Effects
Harmful. Possible risk of harm to the unborn child. Calif. Prop. 65 reproductive hazard. Target organ(s): Central nervous system.
Harmful. Possible risk of harm to the unborn child. Calif. Prop. 65 reproductive hazard. Target organ(s): Central nervous system.
Fire Fighting Measures
Flash Point
277
277
Fire Fighting
Extinguish using Water spray. Carbon dioxide, dry chemical powder, or appropriate foam. Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.
Extinguish using Water spray. Carbon dioxide, dry chemical powder, or appropriate foam. Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.
Stability and Reactivity
Stability
Stable at normal temperatures and pressures.
Stable at normal temperatures and pressures.
Incompatibilities
Strong oxidizing agents.
Strong oxidizing agents.
Decomposition
Carbon monoxide, Carbon dioxide, Nitrogen oxides, Hydrogen chloride gas.
Carbon monoxide, Carbon dioxide, Nitrogen oxides, Hydrogen chloride gas.