Supplier Product Identification Physical and Chemical Properties First Aid Measures Handling and Storage Hazards Identification Exposure Controls/Personal Protection Fire Fighting Measures Accidental Release Measures Stability and Reactivity
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(R)-2-(Methylamino)succinic acid(6384-92-5)

Supplier Product Identification Physical and Chemical Properties First Aid Measures Handling and Storage Hazards Identification Exposure Controls/Personal Protection Fire Fighting Measures Accidental Release Measures Stability and Reactivity

Product Identification

Product Name
(R)-2-(Methylamino)succinic acid
Synonyms
(2R)-2-Methylaminobutanedioic acid
NMDA
N-Methyl D-aspartate
CAS
6384-92-5
Formula
C5H9NO4
Molecular Weight
147.13
RTECS
CI9457000
RTECS Class
Drug
Merck
12,6760
Beilstein/Gmelin
1724431
Beilstein Reference
3-04-00-01522

Physical and Chemical Properties

Appearance
White powder.
Solubility in water
Very soluble
Melting Point
192 - 194
pKa/pKb
2.28 (pKa)
Partition Coefficient
-1.15
Usage
An amino acid that, as the d-isomer, is the defining agonist for the nmda receptor subtype of glutamate receptors.

First Aid Measures

Ingestion
Get medical aid. Wash mouth out with water.
Inhalation
Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Skin
Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes.
Eyes
Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.

Handling and Storage

Storage
Store in a cool, dry place. Do not store in direct sunlight. Store in a tightly closed container.
Handling
Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes.

Hazards Identification

Ingestion
May cause irritation of the digestive tract. May be harmful if swallowed. May cause salicylism with effects similar to skin
Inhalation
May cause respiratory tract irritation. May be harmful if inhaled. May cause salicylism with effects similar skin absorption.
Skin
May cause skin irritation. May be harmful if absorbed through the skin. Absorption through the skin may cause salicylism, characterized by deep and rapid breathing, nausea, vomiting, tinnitis, gastrointestinal irritation with possible ulcers and possible strokes.
Eyes
May cause eye irritation.

Exposure Controls/Personal Protection

Personal Protection
Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.

Fire Fighting Measures

Fire Fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. To extinguish fire use water spray, dry chemical, carbon dioxide, or chemical foam.

Accidental Release Measures

Small spills/leaks
Vacuum or sweep up material and place into a suitable disposal container.

Stability and Reactivity

Stability
No data.
Incompatibilities
Strong oxidizing agents.
Decomposition
Nitrogen oxides, carbon monoxide, carbon dioxide.
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