Supplier Product Identification Physical and Chemical Properties First Aid Measures Handling and Storage Hazards Identification Exposure Controls/Personal Protection Fire Fighting Measures Accidental Release Measures Stability and Reactivity
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18-beta-Glycyrrhetinic acid(471-53-4)

Supplier Product Identification Physical and Chemical Properties First Aid Measures Handling and Storage Hazards Identification Exposure Controls/Personal Protection Fire Fighting Measures Accidental Release Measures Stability and Reactivity

Product Identification

Product Name
18-beta-Glycyrrhetinic acid
Synonyms
Arthrodont
Enoxolone
Glycyrrhetin
Olean-12-en-29-oic acid, 3-hydroxy-11-oxo-, (3b,20b)-
Subglycyrrhelinic acid
Uralenic acid
CAS
471-53-4
Formula
C30H46O4
Molecular Weight
470.69
EINECS
207-444-6
RTECS
RK0180000
RTECS Class
Other
Merck
12,3628
Beilstein/Gmelin
2229654
Beilstein Reference
4-10-00-03775

Physical and Chemical Properties

Appearance
White to gray white solid.
Solubility in water
Insoluble
Melting Point
327 - 330
pKa/pKb
4.71 (pKa)
Usage
Expectorant and antitussive.

First Aid Measures

Ingestion
Get medical aid. Wash mouth out with water.
Inhalation
Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Skin
Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes.
Eyes
Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.

Handling and Storage

Storage
Store in a cool, dry place. Store in a tightly closed container. Refrigerator (approx 4 C).
Handling
Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes.

Hazards Identification

Ingestion
May cause irritation of the digestive tract. May be harmful if swallowed.
Inhalation
May cause respiratory tract irritation. May be harmful if inhaled.
Skin
May cause skin irritation. May be harmful if absorbed through the skin.
Eyes
May cause eye irritation.

Exposure Controls/Personal Protection

Personal Protection
Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Poison Class
4

Fire Fighting Measures

Fire Fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. To extinguish fire use water spray, dry chemical, carbon dioxide, or chemical foam.

Accidental Release Measures

Small spills/leaks
Vacuum or sweep up material and place into a suitable disposal container.

Stability and Reactivity

Stability
Stable under normal temperatures and pressures.
Incompatibilities
Strong acids, strong bases, oxygen.
Decomposition
Carbon monoxide, carbon dioxide.
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