Supplier Product Identification Physical and Chemical Properties First Aid Measures Handling and Storage Hazards Identification Exposure Controls/Personal Protection Fire Fighting Measures Accidental Release Measures Stability and Reactivity
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Flurandrenolide(1524-88-5)

Supplier Product Identification Physical and Chemical Properties First Aid Measures Handling and Storage Hazards Identification Exposure Controls/Personal Protection Fire Fighting Measures Accidental Release Measures Stability and Reactivity

Product Identification

Product Name
Flurandrenolide
Synonyms
6a-Fluoro-11b,16a,17,21-tetrahydroxypregn-4-ene-3,20-dione 16,17-acetonide
Cordran
Drenison
Fluorandrenolone
Pregn-4-ene-3,20-dione, 6-fluoro-11,21-dihydroxy-16,17-((1-methylethylidene)bis(oxy))-, (6alpha,11beta,16alpha)-
CAS
1524-88-5
Formula
C24H33FO6
Molecular Weight
436.52
EINECS
216-196-8
RTECS
TU5024800
RTECS Class
Drug; Mutagen; Hormone
Merck
12,4232
Beilstein/Gmelin
1442935
Beilstein Reference
5-19-06-00547

Physical and Chemical Properties

Solubility in water
Insoluble
Melting Point
209 - 219
Boiling Point
579
Vapor Pressure
8E-16 (25 C)
pKa/pKb
12.84 (pKa)
Heat Of Vaporization
99.5 kJ/mol
Usage
Used to treat the itching, redness, dryness, crusting, scaling, inflammation, and discomfort of various skin conditions.

First Aid Measures

Ingestion
If swallowed, wash out mouth with water provided person is conscious. Call a physician.
Inhalation
If inhaled, remove to fresh air. If not breathing give artificial respiration. If breathing is difficult, give oxygen.

Handling and Storage

Storage
Keep tightly closed. Store in a cool dry place.

Hazards Identification

Inhalation
Material may be irritating to mucous membranes and upper respiratory tract.
Skin
May cause skin irritation. Readily absorbed through skin.
Eyes
May cause eye irritation.
Hazards
Emits toxic fumes under fire conditions.

Exposure Controls/Personal Protection

Personal Protection
Wear appropriate government approved respirator, chemical-resistant gloves, safety goggles, other protective clothing.
Exposure Effects
Properties of this material have not yet been prepared. Any recommendations are of a general nature. Many chemicals cause irritation of the eyes, skin, and respiratory tract. In severe cases respiratory tract irritation can progress to ARDS/acute lung injury which may be delayed in onset for up to 24 to 72 hours in some cases Irritation or burns of the esophagus or gastrointestinal tract are also possible if caustic or irritant chemicals are ingested. ALWAYS contact your local poision control authority or medical professional for assistance.

Fire Fighting Measures

Flash Point
304
Fire Fighting
Extinguish using Noncombustible. Use extinguishing media appropriate to surrounding fire conditions. Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.

Accidental Release Measures

Small spills/leaks
Sweep up, place in a bag and hold for waste disposal. Avoid raising dust. Ventilate area and wash spill site after material pickup is complete.

Stability and Reactivity

Stability
Stable at normal temperatures and pressures.
Incompatibilities
Strong oxidizing agents.
Decomposition
Carbon monoxide, Carbon dioxide, Hydrogen fluoride.
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