Supplier Product Identification Physical and Chemical Properties First Aid Measures Handling and Storage Hazards Identification Exposure Controls/Personal Protection Fire Fighting Measures Accidental Release Measures Stability and Reactivity
Home > (3alpha,5beta,12alpha)-3,12-Dihydroxy-cholan-24-oic acid > (3alpha,5beta,12alpha)-3,12-Dihydroxy-cholan-24-oic acid(83-44-3)

(3alpha,5beta,12alpha)-3,12-Dihydroxy-cholan-24-oic acid(83-44-3)

Supplier Product Identification Physical and Chemical Properties First Aid Measures Handling and Storage Hazards Identification Exposure Controls/Personal Protection Fire Fighting Measures Accidental Release Measures Stability and Reactivity

Product Identification

Product Name
(3alpha,5beta,12alpha)-3,12-Dihydroxy-cholan-24-oic acid
Synonyms
1,3-Isobenzofurandione, hexahydro-5-methyl-
17b-[1-Methyl-3-carboxypropyl]-etiocholane-3a,12a-diol
3a,12a-Dihydroxy-5b-cholanic acid
5-Methyl-3a,4,5,6,7,7a-hexahydro-2-benzofuran-1,3-dione
Cholan-24-oic acid, 3,12-dihydroxy-, (3a,5b,12a)-
Degalol
Hexahydro-4-methylphthalic anhydride
Pyrochol
Septochol
CAS
83-44-3
CAS
19438-60-9
Formula
C24H40O4
Formula
C9H12O3
Molecular Weight
168.19
Molecular Weight
392.58
EINECS
201-478-5
EINECS
243-072-0
RTECS
FZ2100000
RTECS Class
Tumorigen; Mutagen; Reproductive Effector
Merck
13,2916
Beilstein/Gmelin
83443
Beilstein/Gmelin
3219882
Beilstein Reference
4-10-00-01608
Beilstein Reference
5-17-11-00083
EC Index Number
607-241-00-6
EC Class
Irritant; Sensitising

Physical and Chemical Properties

Appearance
Colorless to light yellow liquid.
Appearance
White solid.
Solubility in water
Insoluble
Solubility in water
Slightly soluble
Melting Point
190
Boiling Point
300
Boiling Point
504
Vapor Pressure
0.0012 (25 C)
Density
1.16 g/cm3
pKa/pKb
4.76 (pKa)
Partition Coefficient
.73
Partition Coefficient
4.2
Heat Of Vaporization
54.0 kJ/mol
Usage
Emulsifying agent in food, precursor for organic synthesis of cortisone.

First Aid Measures

Ingestion
Do NOT induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid.
Ingestion
Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
Inhalation
Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid if cough or other symptoms appear.
Inhalation
Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Inhalation
Causes respiratory tract irritation. The toxicological properties of this substance have not been fully investigated.
Skin
Causes skin irritation. The toxicological properties of this material have not been fully investigated.
Skin
Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Get medical aid if irritation develops or persists.
Skin
Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
Eyes
Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Eyes
Causes eye irritation.

Handling and Storage

Storage
Store in a cool, dry place. Store in a tightly closed container.
Storage
Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Store protected from moisture.
Handling
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Use with adequate ventilation. Do not allow contact with water. Wash clothing before reuse. Keep from contact with moist air and steam.
Handling
Wash thoroughly after handling. Wash hands before eating. Use only in a well ventilated area. Avoid contact with skin and eyes. Do not breathe dust, vapor, mist, or gas. Do not ingest or inhale.

Hazards Identification

Ingestion
May cause gastrointestinal irritation with nausea, vomiting and diarrhea. May be harmful if swallowed.
Ingestion
Causes gastrointestinal irritation with nausea, vomiting and diarrhea. The toxicological properties of this substance have not been fully investigated.
Inhalation
Dust is irritating to the respiratory tract.
Skin
May cause skin irritation.
Eyes
May cause eye irritation.
EC Risk Phrase
R 22 36/37/38
EC Safety Phrase
S 22 26 36/37/39

Exposure Controls/Personal Protection

Personal Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate gloves to prevent skin exposure. Clothing: Wear appropriate clothing to prevent skin exposure.
Personal Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Poison Class
4

Fire Fighting Measures

Flash Point
140
Fire Fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Containers may explode when heated. Extinguishing media: Do NOT get water inside containers. In case of fire use water spray, dry chemical, carbon dioxide, or appropriate foam.
Fire Fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. To extinguish fire use water spray, dry chemical, carbon dioxide, or chemical foam.

Accidental Release Measures

Small spills/leaks
Absorb spill with inert material, (e.g., dry sand or earth), then place into a chemical waste container. Avoid runoff into storm sewers and ditches which lead to waterways. Clean up spills immediately, using the appropriate protective equipment. Provide ventilation. Do not get water inside containers.
Small spills/leaks
Vacuum or sweep up material and place into a suitable disposal container. Reduce airborne dust and prevent scattering by moistening with water. Clean up spills immediately, using the appropriate protective equipment.

Stability and Reactivity

Incompatibilities
Moisture, strong acids, strong bases, strong oxidizing agents.
Stability
Stable at room temperature in closed containers under normal storage and handling conditions.
Stability
Stable under normal temperatures and pressures.
Incompatibilities
Strong oxidizing agents.
Decomposition
Carbon monoxide, carbon dioxide.
Decomposition
Carbon monoxide, irritating and toxic fumes and gases, carbon dioxide.
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