Supplier Product Identification Physical and Chemical Properties First Aid Measures Handling and Storage Hazards Identification Exposure Controls/Personal Protection Fire Fighting Measures Accidental Release Measures Stability and Reactivity Transport Information
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Penfluridol(26864-56-2)

Supplier Product Identification Physical and Chemical Properties First Aid Measures Handling and Storage Hazards Identification Exposure Controls/Personal Protection Fire Fighting Measures Accidental Release Measures Stability and Reactivity Transport Information

Product Identification

Product Name
Penfluridol
Synonyms
1-[4,4-Bis(4-fluorophenyl)butyl]-4-[4-chloro-3(trifluoromethyl)phenyl]-4-piperidinol
1-[4,4-Bis(4-fluorophenyl)butyl]-4-[4-chloro-3-(trifluoromethyl)phenyl]piperidin-4-ol
R 16341
Semap
CAS
26864-56-2
Formula
C28H27ClF5NO
Molecular Weight
523.97
EINECS
248-074-5
RTECS
TN6957000
RTECS Class
Drug; Reproductive Effector
Merck
12,7213
Beilstein/Gmelin
1558826
Beilstein Reference
5-21-02-00409

Physical and Chemical Properties

Appearance
White powder.
Solubility in water
Insoluble
Boiling Point
588
Vapor Pressure
1E-14 (14 C)
pKa/pKb
5.55 (pKb)
Heat Of Vaporization
92.3 kJ/mol
Usage
T-type ca channel blocker; antipsychotic.

First Aid Measures

Ingestion
If swallowed, wash out mouth with water provided person is conscious. Call a physician immediately.
Inhalation
If inhaled, remove to fresh air. If not breathing give artificial respiration. If breathing is difficult, give oxygen.
Skin
In case of skin contact, flush with copious amounts of water for at least 15 minutes. Remove contaminated clothing and shoes. Call a physician.
Eyes
In case of contact with eyes, flush with copious amounts of water for at least 15 minutes. Assure adequate flushing by separating the eyelids with fingers. Call a physician.

Handling and Storage

Storage
Keep tightly closed.

Hazards Identification

Inhalation
Material may be irritating to mucous membranes and upper respiratory tract. May be harmful if inhaled.
Skin
May cause skin irritation. May be harmful if absorbed through the skin.
Eyes
May cause eye irritation.
Ingestion
Toxic if swallowed.
Hazards
Emits toxic fumes under fire conditions.
EC Risk Phrase
25
EC Safety Phrase
45
UN (DOT)
2811

Exposure Controls/Personal Protection

Personal Protection
Compatible chemical-resistant gloves. Chemical safety goggles.
Respirators
Government approved respirator.
Exposure Effects
Toxic. Toxic if swallowed.

Fire Fighting Measures

Flash Point
309
Fire Fighting
Extinguish using Water spray. Carbon dioxide, dry chemical powder, or appropriate foam. Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.
Fire Potential
Non-combustible, substance itself does not burn but may decompose upon heating to produce corrosive and/or toxic fumes.

Accidental Release Measures

Small spills/leaks
Sweep up, place in a bag and hold for waste disposal. Avoid raising dust. Ventilate area and wash spill site after material pickup is complete.

Stability and Reactivity

Stability
Stable at normal temperatures and pressures.
Incompatibilities
Strong oxidizing agents.
Decomposition
Thermal decomposition may produce carbon monoxide, carbon dioxide, and nitrogen oxides, Hydrogen chloride gas, Hydrogen fluoride.
Combustion Products
Fire may produce irritating, corrosive and/or toxic gases.

Transport Information

UN Number
2811
Hazard Class
6.1
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