Supplier Product Identification Physical and Chemical Properties First Aid Measures Handling and Storage Hazards Identification Exposure Controls/Personal Protection Fire Fighting Measures Accidental Release Measures Stability and Reactivity Transport Information
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5-Fluoropyrimidine-2,4-dione(51-21-8)

Supplier Product Identification Physical and Chemical Properties First Aid Measures Handling and Storage Hazards Identification Exposure Controls/Personal Protection Fire Fighting Measures Accidental Release Measures Stability and Reactivity Transport Information

Product Identification

Product Name
5-Fluoropyrimidine-2,4-dione
Synonyms
5-Fluoro-1H-pyrimidine-2,4-dione
5-Fluoro-2,4(1H,3H)-pyrimidinedione
CAS
51-21-8
Formula
C4H3FN2O2
Molecular Weight
130.08000000000001
EINECS
200-085-6
RTECS
YR0350000
RTECS Class
Tumorigen; Drug; Mutagen; Reproductive Effector; Human Data; Primary Irritant
Merck
13,4208
Beilstein/Gmelin
127172
Beilstein Reference
5-34-06-00271
EC Class
harmful

Physical and Chemical Properties

Appearance
White to nearly white crystalline powder; practically odorless.
Solubility in water
Very soluble
Melting Point
282 - 283
Boiling Point
347
pKa/pKb
7.88 (pKa)
Partition Coefficient
-.78
Heat Of Vaporization
Usage
Immunosuppressive agent.

First Aid Measures

Ingestion
Get medical aid. Wash mouth out with water.
Inhalation
Remove from exposure to fresh air immediately. Get medical aid.
Skin
Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes.
Eyes
Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.

Handling and Storage

Storage
Store in a cool, dry place. Store in a tightly closed container.
Handling
Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes. Store protected from light. Use only in a chemical fume hood.

Hazards Identification

Inhalation
Harmful if inhaled. Causes respiratory tract irritation.
Skin
Causes skin irritation. Harmful if absorbed through the skin.
Eyes
May cause eye irritation.
Ingestion
Harmful if swallowed. Causes gastrointestinal irritation with nausea, vomiting and diarrhea.
Hazards
Emits very toxic fumes of flourides and nitrogen oxides when heated to decomposition. Avoid decomposing heat.
EC Risk Phrase
R 46 60 61 23/24/25
EC Safety Phrase
S 53 45
UN (DOT)
2811

Exposure Controls/Personal Protection

Personal Protection
Eyes: Wear chemical goggles. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear a chemical apron.
Respirators
A NIOSH/MSHA approved air purifying dust or mist respirator or European Standard EN 149.
Exposure Effects
Prolonged or repeated exposure may cause adverse reproductive effects.
Poison Class
1*

Fire Fighting Measures

Flash Point
280
Fire Fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Extinguishing media: Use water spray, dry chemical, or carbon dioxide.

Accidental Release Measures

Small spills/leaks
Vacuum or sweep up material and place into a suitable disposal container.

Stability and Reactivity

Disposal Code
3
Stability
Stable under normal temperatures and pressures.
Incompatibilities
Strong oxidizing agents.
Decomposition
Nitrogen oxides, carbon monoxide, carbon dioxide, hydrogen fluoride.

Transport Information

UN Number
2811
HS Code
2933 59 95
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