Supplier Product Identification Physical and Chemical Properties First Aid Measures Handling and Storage Hazards Identification Exposure Controls/Personal Protection Fire Fighting Measures Accidental Release Measures Stability and Reactivity
Home > S-2-Hydroxymethyl-pyrrolidine > S-2-Hydroxymethyl-pyrrolidine(23356-96-9)

S-2-Hydroxymethyl-pyrrolidine(23356-96-9)

Supplier Product Identification Physical and Chemical Properties First Aid Measures Handling and Storage Hazards Identification Exposure Controls/Personal Protection Fire Fighting Measures Accidental Release Measures Stability and Reactivity

Product Identification

Product Name
S-2-Hydroxymethyl-pyrrolidine
Synonyms
(2S)-2-(Hydroxymethyl)pyrrolidine
(2S)-2-Pyrrolidinemethanol
[(2S)-Pyrrolidin-2-yl]methanol
2-Pyrrolidinemethanol, (S)-
L-(Pyrrolidin-1-yl)methanol
L-2-(Hydroxymethyl)pyrrolidine
CAS
23356-96-9
Formula
C5H11NO
Molecular Weight
101.14
EINECS
245-605-2
Beilstein/Gmelin
79843
Beilstein Reference
5-21-01-00077

Physical and Chemical Properties

Appearance
Colorless viscous liquid.
Solubility in water
Very soluble
Boiling Point
75
Density
1.025 g/cm3
pKa/pKb
3.44 (pKb)
Usage
Used as a chiral building block in organic synthesis.
Vapor Density
3.49
Refractive Index
1.4878 (20 C)

First Aid Measures

Ingestion
Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
Inhalation
Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Skin
Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
Eyes
Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.

Handling and Storage

Storage
Keep away from heat, sparks, and flame. Keep away from sources of ignition. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Refrigerator (approx 4 C). Do not expose to air. Store protected from moisture. Store under an inert atmosphere.
Handling
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use only in a well ventilated area. Avoid contact with eyes, skin, and clothing. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Keep container tightly closed. Avoid contact with heat, sparks and flame. Avoid ingestion and inhalation. Handle under an inert atmosphere. Store protected from air. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames.

Hazards Identification

Ingestion
May cause gastrointestinal irritation with nausea, vomiting and diarrhea.
Inhalation
Causes respiratory tract irritation. Aspiration may lead to pulmonary edema. Inhalation at high concentrations may cause CNS depression and asphixiation.
Skin
Causes skin irritation. May cause irritation and dermatitis. May cause cyanosis of the extremities.
Eyes
Causes eye irritation. May cause chemical conjunctivitis and corneal damage.
EC Risk Phrase
R 36/38
EC Safety Phrase
S 26 36

Exposure Controls/Personal Protection

Personal Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.

Fire Fighting Measures

Flash Point
86
Fire Fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Use water spray to keep fire-exposed containers cool. Combustible Liquid. Extinguishing media: Use water spray to cool fire-exposed containers. Use agent most appropriate to extinguish fire. In case of fire use water spray, dry chemical, carbon dioxide, or appropriate foam.

Accidental Release Measures

Small spills/leaks
Absorb spill with inert material, (e.g., dry sand or earth), then place into a chemical waste container. Avoid runoff into storm sewers and ditches which lead to waterways. Clean up spills immediately, using the appropriate protective equipment. Remove all sources of ignition. Use a spark-proof tool. Provide ventilation. Place under an inert atmosphere.

Stability and Reactivity

Stability
Stable at room temperature in closed containers under normal storage and handling conditions.
Incompatibilities
Strong oxidizing agents, acid chlorides, acid anhydrides, moisture, air.
Decomposition
Carbon monoxide, oxides of nitrogen, irritating and toxic fumes and gases, carbon dioxide.
Contact More