Supplier Product Identification Physical and Chemical Properties First Aid Measures Handling and Storage Hazards Identification Exposure Controls/Personal Protection Fire Fighting Measures Accidental Release Measures Stability and Reactivity Transport Information
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4'-Hydroxy-3'-methoxyacetophenone(498-02-2)

Supplier Product Identification Physical and Chemical Properties First Aid Measures Handling and Storage Hazards Identification Exposure Controls/Personal Protection Fire Fighting Measures Accidental Release Measures Stability and Reactivity Transport Information

Product Identification

Product Name
4'-Hydroxy-3'-methoxyacetophenone
Synonyms
1-(4-Hydroxy-3-methoxyphenyl)ethanone
4-Acetyl-2-methoxyphenol
4-Acetylguaiacol
4'-Hydroxy-3'-methoxyacetophenone
Acetoguaiacone
Acetovanillone
CAS
498-02-2
Formula
C9H10O3
Molecular Weight
166.18
EINECS
207-854-5
RTECS
AM8800000
RTECS Class
Drug; Mutagen
Merck
13,746
Beilstein/Gmelin
637373
Beilstein Reference
4-08-00-01814

Physical and Chemical Properties

Appearance
Light yellow to yellow solid. Faint vanilla odor.
Solubility in water
Slightly soluble
Melting Point
115
Boiling Point
295
Vapor Pressure
0.0008 (25 C)
pKa/pKb
8.17 (pKa)
Partition Coefficient
1.38
Heat Of Vaporization
55.9 kJ/mol
Usage
A plant-derived, cartilage-saving drug, might be useful in the treatment of rheumatoid arthritis.

First Aid Measures

Ingestion
Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
Inhalation
Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Skin
Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes.
Eyes
Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.

Handling and Storage

Storage
Store in a cool, dry place. Keep container closed when not in use.
Handling
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Avoid contact with eyes, skin, and clothing. Avoid ingestion and inhalation.

Hazards Identification

Ingestion
The toxicological properties of this substance have not been fully investigated.
Inhalation
The toxicological properties of this substance have not been fully investigated.
Skin
May cause skin irritation.
Eyes
May cause eye irritation.
EC Risk Phrase
R 36/37/38
EC Safety Phrase
S 26 36

Exposure Controls/Personal Protection

Personal Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves and clothing to prevent skin exposure. Clothing: Wear appropriate protective clothing to minimize contact with skin.
Respirators
Wear a NIOSH/MSHA or European Standard EN 149 approved full-facepiece airline respirator in the positive pressure mode with emergency escape provisions.

Fire Fighting Measures

Flash Point
126
Fire Fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. To extinguish fire, use water, dry chemical, chemical foam, or alcohol-resistant foam.

Accidental Release Measures

Small spills/leaks
Clean up spills immediately, using the appropriate protective equipment. Sweep up, then place into a suitable container for disposal.

Stability and Reactivity

Stability
Stable under normal temperatures and pressures.
Incompatibilities
Strong oxidants.
Decomposition
Carbon monoxide, irritating and toxic fumes and gases, carbon dioxide.

Transport Information

HS Code
2914 50 00
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