Supplier Product Identification Physical and Chemical Properties First Aid Measures Handling and Storage Hazards Identification Exposure Controls/Personal Protection Fire Fighting Measures Accidental Release Measures Stability and Reactivity
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2'-Deoxy-5-iodouridine(54-42-2)

Supplier Product Identification Physical and Chemical Properties First Aid Measures Handling and Storage Hazards Identification Exposure Controls/Personal Protection Fire Fighting Measures Accidental Release Measures Stability and Reactivity

Product Identification

Product Name
2'-Deoxy-5-iodouridine
Synonyms
(+)-5-Iodo-2'-deoxyuridine
1-[(2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-iodopyrimidine-2,4-dione
Herplex
Idoxuridine
CAS
54-42-2
Formula
C9H11IN2O5
Molecular Weight
354.1
EINECS
200-207-8
RTECS
YU7700000
RTECS Class
Tumorigen; Drug; Mutagen; Reproductive Effector
Merck
12,4934
Beilstein/Gmelin
30397
Beilstein Reference
4-24-00-01235

Physical and Chemical Properties

Appearance
White powder.
Solubility in water
2.0 mg/ml
Melting Point
164 - 166
Boiling Point
531
pKa/pKb
8.25(at 25℃) (pKa)
Partition Coefficient
-.63
Usage
Used as an antiviral agent.

First Aid Measures

Ingestion
Get medical aid. Wash mouth out with water.
Inhalation
Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Skin
Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes.
Eyes
Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.

Handling and Storage

Storage
Store in a cool, dry place. Store in a tightly closed container.
Handling
Do not breathe dust, vapor, mist, or gas. Do not get in eyes, on skin, or on clothing. Use only in a chemical fume hood.

Hazards Identification

Ingestion
Harmful if swallowed. May cause irritation of the digestive tract.
Inhalation
Harmful if inhaled. May cause respiratory tract irritation. Causes irritation of mucous membrane.
Skin
May cause skin irritation. Harmful if absorbed through the skin.
Eyes
May cause eye irritation.

Exposure Controls/Personal Protection

Personal Protection
Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.

Fire Fighting Measures

Autoignition
350
Fire Fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. To extinguish fire use water spray, dry chemical, carbon dioxide, or chemical foam.

Accidental Release Measures

Small spills/leaks
Sweep up, then place into a suitable container for disposal. Avoid generating dusty conditions.

Stability and Reactivity

Stability
Stable under normal temperatures and pressures.
Incompatibilities
Strong oxidizing agents.
Decomposition
Nitrogen oxides, carbon monoxide, carbon dioxide, hydrogen iodide.
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