Supplier Product Identification Physical and Chemical Properties First Aid Measures Handling and Storage Hazards Identification Exposure Controls/Personal Protection Fire Fighting Measures Accidental Release Measures Stability and Reactivity
Home > 6-(1-Piperidinyl)-2,4-pyrimidinediamine-3-oxide > 6-(1-Piperidinyl)-2,4-pyrimidinediamine-3-oxide(38304-91-5)

6-(1-Piperidinyl)-2,4-pyrimidinediamine-3-oxide(38304-91-5)

Supplier Product Identification Physical and Chemical Properties First Aid Measures Handling and Storage Hazards Identification Exposure Controls/Personal Protection Fire Fighting Measures Accidental Release Measures Stability and Reactivity

Product Identification

Product Name
6-(1-Piperidinyl)-2,4-pyrimidinediamine-3-oxide
Synonyms
2,3-Dihydro-3-hydroxy-2-Imino-6-(1-piperidinyl)-4-pyrimidinamine
2,4-Diamino-6-piperidinopyrimidine 3-oxide
6-Amino-1,2-dihydro-1-hydroxy-2-Imino-4-piperidinopyrimidine
Aalopexil
Alostil
U-10,858
CAS
38304-91-5
Formula
C9H15N5O
Molecular Weight
209.25
EINECS
253-874-2
RTECS
UV8200000
RTECS Class
Drug; Reproductive Effector; Human Data
Merck
12,6290
Beilstein/Gmelin
886240
Beilstein Reference
5-25-12-00317

Physical and Chemical Properties

Appearance
Crystals from methanol-acetonitrile. Odorless. Solutions are colorless to light yellow.
Melting Point
248
pKa/pKb
4.61 (pKa)
Usage
Medication.

First Aid Measures

Ingestion
Immediately seek medical assistance.
Inhalation
Remove from exposure. Seek medical assistance.
Skin
Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes.
Eyes
Flush eyes with copious amounts of water. Seek medical assistance.

Handling and Storage

Storage
Keep in a cool, dry location. Keep containers closed when not in use. Protect from light.
Handling
All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.

Hazards Identification

Inhalation
Pulmonary edema has been reported following buflomedil overdoses. Respiratory depression may occur with buflomedil intoxication.
Skin
May cause irritation, allergic contact dermatitis.
Eyes
Burns, irritation.
Ingestion
Nausea and vomiting are common following therapeutic administration of fenoldopam.

Exposure Controls/Personal Protection

Personal Protection
Chemical splash goggles in compliance with OSHA regulations are advised; however, OSHA regulations also permit other type safety glasses. Whre chemical resistant gloves. To prevent repeated or prolonged skin contact, wear impervious clothing and boots.
Respirators
Use NIOSH/MSHA approved respirator appropriate for exposure of concern.
Exposure Effects
Headache, dizziness and sweating may occur with any of the vasodilators. Peripheral neuropathy has been reported following long term hydralazine therapy. Hyperglycemic, non-ketotic coma may occur with diazoxide. Seizures and coma may occur with buflomedil toxicity.

Fire Fighting Measures

Fire Fighting
Extinguish using water, carbon dixoide or dry chemical powder. Use a SCBA and full-body protective equipment.

Accidental Release Measures

Small spills/leaks
Absorb spilled solutions wiht papter towls or other appropriate media. For solid, sweep up. Transfer to suitable container for later disposal.

Stability and Reactivity

Stability
Stable at normal temperatures and pressures.
Contact More