Supplier Product Identification Physical and Chemical Properties First Aid Measures Handling and Storage Hazards Identification Exposure Controls/Personal Protection Fire Fighting Measures Accidental Release Measures Stability and Reactivity
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4',7-Dihydroxyisoflavone(486-66-8)

Supplier Product Identification Physical and Chemical Properties First Aid Measures Handling and Storage Hazards Identification Exposure Controls/Personal Protection Fire Fighting Measures Accidental Release Measures Stability and Reactivity

Product Identification

Product Name
4',7-Dihydroxyisoflavone
Synonyms
7-Hydroxy-3-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
7-Hydroxy-3-(4-hydroxyphenyl)chromen-4-one
CAS
486-66-8
Formula
C15H10O4
Molecular Weight
254.24
EINECS
207-635-4
RTECS
DJ3100040
RTECS Class
Drug
Merck
13,2829
Beilstein/Gmelin
231523
Beilstein Reference
5-18-04-00089

Physical and Chemical Properties

Appearance
Almost white solid.
Solubility in water
Insoluble
Melting Point
212 - 214
Boiling Point
513
Vapor Pressure
4E-11 (25 C)
pKa/pKb
7.54
Partition Coefficient
2.97
Heat Of Vaporization
81.4 kJ/mol
Usage
Used to evaluate time-resolved fluoroimmunoassay for determination of daidzein in plasma (serum).

First Aid Measures

Ingestion
Get medical aid. Wash mouth out with water.
Inhalation
Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Skin
Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes.
Eyes
Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.

Handling and Storage

Storage
Store in a tightly closed container. Deep freeze (below -20 C).
Handling
Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes.

Hazards Identification

Ingestion
May cause irritation of the digestive tract. May be harmful if swallowed. May cause headache, drowsiness, and
Inhalation
Causes respiratory tract irritation. May be harmful if inhaled. Exposure to high concentrations may cause narcosis.
Skin
Causes skin irritation. May be harmful if absorbed through the skin.
Eyes
Causes eye irritation.
EC Risk Phrase
R 36/37/38
EC Safety Phrase
S 26 36

Exposure Controls/Personal Protection

Personal Protection
Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.

Fire Fighting Measures

Flash Point
201
Fire Fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. To extinguish fire use water spray, dry chemical, carbon dioxide, or chemical foam.

Accidental Release Measures

Small spills/leaks
Vacuum or sweep up material and place into a suitable disposal container.

Stability and Reactivity

Stability
Stable under normal shipping and handling conditions.
Incompatibilities
Sterk oxyderend middel.
Decomposition
Carbon monoxide, carbon dioxide.
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