Supplier Product Identification Physical and Chemical Properties First Aid Measures Handling and Storage Hazards Identification Exposure Controls/Personal Protection Fire Fighting Measures Accidental Release Measures Stability and Reactivity
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2-Hydroxy-4-amino-5-fluoropyrimidine(2022-85-7)

Supplier Product Identification Physical and Chemical Properties First Aid Measures Handling and Storage Hazards Identification Exposure Controls/Personal Protection Fire Fighting Measures Accidental Release Measures Stability and Reactivity

Product Identification

Product Name
2-Hydroxy-4-amino-5-fluoropyrimidine
Synonyms
4-Amino-5-fluoro-2(1H)-pyrimidinone
4-Amino-5-fluoro-3H-pyrimidin-2-one
Alcobon
Ancobon
Ancotil
Flucytosine
CAS
2022-85-7
Formula
C4H4FN3O
Molecular Weight
129.09
EINECS
217-968-7
RTECS
HA6040000
RTECS Class
Drug; Mutagen; Human Data
Merck
13,4151
Beilstein/Gmelin
127285
Beilstein Reference
4-25-00-03688

Physical and Chemical Properties

Solubility in water
15 g/L
Melting Point
165
Boiling Point
298
pKa/pKb
3.26(at 25℃) (pKa)
Partition Coefficient
-1.07
Usage
Medication.

First Aid Measures

Ingestion
Get medical aid. Wash mouth out with water.
Inhalation
Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.
Skin
Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Get medical aid if irritation develops or persists.
Eyes
Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. If irritation develops, get medical aid.

Handling and Storage

Storage
Store in a cool, dry place. Store in a tightly closed container.
Handling
Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes. Store protected from light.

Hazards Identification

Inhalation
May cause respiratory tract irritation.
Skin
May cause skin irritation.
Eyes
May cause eye irritation.
Ingestion
No hazard expected in normal industrial use.
EC Risk Phrase
R 40
EC Safety Phrase
S 22 36/37

Exposure Controls/Personal Protection

Personal Protection
Eyes: Wear chemical goggles. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear a chemical apron.
Respirators
A NIOSH/MSHA approved air purifying dust or mist respirator or European Standard EN 149.
Exposure Effects
Prolonged or repeated exposure may cause adverse reproductive effects.

Fire Fighting Measures

Flash Point
296
Fire Fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. To extinguish fire use water spray, dry chemical, carbon dioxide, or chemical foam.

Accidental Release Measures

Small spills/leaks
Vacuum or sweep up material and place into a suitable disposal container.

Stability and Reactivity

Stability
No data.
Incompatibilities
Strong oxidizing agents.
Decomposition
Nitrogen oxides, carbon monoxide, carbon dioxide, hydrogen fluoride.
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