Supplier Product Identification Physical and Chemical Properties First Aid Measures Handling and Storage Exposure Controls/Personal Protection Fire Fighting Measures Accidental Release Measures Stability and Reactivity Hazards Identification
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o-Sialic acid(131-48-6)

Supplier Product Identification Physical and Chemical Properties First Aid Measures Handling and Storage Exposure Controls/Personal Protection Fire Fighting Measures Accidental Release Measures Stability and Reactivity Hazards Identification

Product Identification

Product Name
o-Sialic acid
Synonyms
(2S,4S,5R,6R)-5-Acetamido-2,4-dihydroxy-6-(1,2,3-trihydroxypropyl)oxane-2-carboxylic acid
5-N-Acetyl-D-neuraminic acid
D-glycero-D-galacto-Nonulosonic acid, 5-acetamido-3,5-dideoxy-
N-Acetylneuraminic acid
N-Acetylsialic acid
Sialomucin
CAS
131-48-6
Formula
C11H19NO9
Molecular Weight
309.27
EINECS
205-023-1
Merck
12,8628
Beilstein/Gmelin
1716283
Beilstein Reference
4-04-00-03288

Physical and Chemical Properties

Solubility in water
Very soluble
Melting Point
185 - 187
pKa/pKb
2.41 (pKa)
Partition Coefficient
-3.19
Usage
An n-acyl derivative of neuraminic acid. N-acetylneuraminic acid occurs in many polysaccharides, glycoproteins, and glycolipids in animals and bacteria.

First Aid Measures

Ingestion
Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
Inhalation
Remove from exposure to fresh air immediately.
Skin
Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes.
Eyes
Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids.

Handling and Storage

Storage
Store in a cool, dry place. Keep container closed when not in use. Deep freeze (below -20 C).
Handling
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Avoid contact with eyes, skin, and clothing. Avoid ingestion and inhalation.

Exposure Controls/Personal Protection

Personal Protection
Eyes: Wear safety glasses and chemical goggles if splashing is possible. Skin: Wear appropriate protective gloves and clothing to prevent skin exposure. Clothing: Wear appropriate protective clothing to minimize contact with skin.
Respirators
Wear a NIOSH/MSHA or European Standard EN 149 approved full-facepiece airline respirator in the positive pressure mode with emergency escape provisions.
Exposure Effects
The toxicological properties of this material have not been investigated.

Fire Fighting Measures

Flash Point
184
Fire Fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. To extinguish fire, use water, dry chemical, chemical foam, or alcohol-resistant foam.

Accidental Release Measures

Small spills/leaks
Clean up spills immediately, using the appropriate protective equipment. Sweep up, then place into a suitable container for disposal.

Stability and Reactivity

Stability
Stable under normal temperatures and pressures.
Incompatibilities
Strong oxidizing agents.
Decomposition
Irritating and toxic fumes and gases.

Hazards Identification

EC Safety Phrase
S 22 24/25
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