Supplier Product Identification Physical and Chemical Properties First Aid Measures Handling and Storage Hazards Identification Exposure Controls/Personal Protection Fire Fighting Measures Accidental Release Measures Stability and Reactivity
Home > 6a,9a-Fifluoro-16a,17a-isopropylidenedioxy-1,4-pregnadiene-3,20-dione > 6a,9a-Fifluoro-16a,17a-isopropylidenedioxy-1,4-pregnadiene-3,20-dione(67-73-2)

6a,9a-Fifluoro-16a,17a-isopropylidenedioxy-1,4-pregnadiene-3,20-dione(67-73-2)

Supplier Product Identification Physical and Chemical Properties First Aid Measures Handling and Storage Hazards Identification Exposure Controls/Personal Protection Fire Fighting Measures Accidental Release Measures Stability and Reactivity

Product Identification

Product Name
6a,9a-Fifluoro-16a,17a-isopropylidenedioxy-1,4-pregnadiene-3,20-dione
Synonyms
6a,9a-Difluoro-16a-hydroxyprednisolone 16,17-acetonide
6a-Fluorotriamcinolone acetonide
Pregna-1,4-diene-3,20-dione, 6,9-difluoro-11,12-dihydroxy-16, 17-[(1-methylethylidene)bis(oxy)]-, (6.alpha.,11.beta., 16.alpha.)-
Sinalar
Synandone
CAS
67-73-2
Formula
C24H30F2O6
Molecular Weight
452.5
EINECS
200-668-5
RTECS
TU3830000
RTECS Class
Drug; Mutagen; Reproductive Effector
Merck
12,4185
Beilstein/Gmelin
1358395
Beilstein Reference
5-19-06-00571

Physical and Chemical Properties

Solubility in water
Insoluble
Melting Point
267 - 269
Boiling Point
579
Vapor Pressure
9E-16 (25 C)
pKa/pKb
12.55 (pKa)
Heat Of Vaporization
99.4 kJ/mol
Usage
A synthetic steroid used as an anti-inflammatory and anti-pruritic agent.

First Aid Measures

Ingestion
If swallowed, wash out mouth with water provided person is conscious. Call a physician.
Inhalation
If inhaled, remove to fresh air. If not breathing give artificial respiration. If breathing is difficult, give oxygen

Handling and Storage

Storage
Keep tightly closed. Store in a cool dry place.

Hazards Identification

Inhalation
Material is irritating to mucous membranes and upper respiratory tract.
Skin
Causes irritation. Toxic if absorbed through the skin.
Eyes
Causes irritation.
Ingestion
Harmful/toxic if swallowed
Hazards
Emits toxic fumes under fire conditions.
EC Risk Phrase
20/21/22 36/37/38 40
EC Safety Phrase
22 26 36

Exposure Controls/Personal Protection

Personal Protection
Evacuate area. Wear self-contained breathing apparatus, rubber boots, and heavy rubber gloves. Wear disposable coveralls and discard them after use.
Exposure Effects
Limited evidence of a carcinogenic effect Possible teratogen. Possible mutagen.

Fire Fighting Measures

Flash Point
304
Fire Fighting
Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes. Water spray. Carbon dioxide, dry chemical powder, or appropriate foam.

Accidental Release Measures

Small spills/leaks
Sweep up, place in a bag and hold for waste disposal. Avoid raising dust. Ventilate area and wash spill site after material pickup is complete. Do not breathe dust. Do not get in eyes, on skin, on clothing. Avoid prolonged or repeated exposure.

Stability and Reactivity

Incompatibilities
Strong oxidizing agents.
Decomposition
Carbon monoxide, Carbon dioxide, Hydrogen fluoride.
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