Home > 2-Nitroaniline > 2-Nitroaniline(88-74-4)
2-Nitroaniline(88-74-4)
Product Identification
Physical and Chemical Properties
First Aid Measures
Handling and Storage
Hazards Identification
Exposure Controls/Personal Protection
Fire Fighting Measures
Accidental Release Measures
Stability and Reactivity
Transport Information
Product Identification
Product Name
2-Nitroaniline
2-Nitroaniline
Synonyms
1-Amino-2-nitrobenzene
o-Nitroaniline
1-Amino-2-nitrobenzene
o-Nitroaniline
CAS
88-74-4
88-74-4
Formula
C6H6N2O2
C6H6N2O2
Molecular Weight
138.13
138.13
EINECS
201-855-4
201-855-4
RTECS
BY6650000
BY6650000
RTECS Class
Mutagen
Mutagen
Merck
12,6680
12,6680
Beilstein/Gmelin
509275
509275
Beilstein Reference
4-12-00-01563
4-12-00-01563
EC Index Number
612-012-00-9
612-012-00-9
EC Class
Toxic; Danger of cumulative effects; Dangerous for the Environment
Toxic; Danger of cumulative effects; Dangerous for the Environment
Physical and Chemical Properties
Appearance
Orange solid with a musty odor.
Orange solid with a musty odor.
Solubility in water
1.1 g/L
1.1 g/L
Melting Point
68 - 71
68 - 71
Boiling Point
284
284
Vapor Pressure
0.003 (25 C)
0.003 (25 C)
Density
1.446 g/cm3 (20 C)
1.446 g/cm3 (20 C)
pKa/pKb
-0.26(at 25℃) (pKa)
-0.26(at 25℃) (pKa)
Partition Coefficient
1.83
1.83
Heat Of Vaporization
52.4 kJ/mol
52.4 kJ/mol
Heat Of Combustion
-3029 kJ/mol
-3029 kJ/mol
Usage
Chemical intermediate for ci pigment yellow 5, orange 2, yellow 7, vat red 15, vat orange 7, ci pigment orange 43, vat red 14, disperse yellow 10.
Chemical intermediate for ci pigment yellow 5, orange 2, yellow 7, vat red 15, vat orange 7, ci pigment orange 43, vat red 14, disperse yellow 10.
Refractive Index
1.5362 (100 C)
1.5362 (100 C)
First Aid Measures
Ingestion
If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.
If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.
Inhalation
Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Skin
Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes.
Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes.
Eyes
Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.
Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.
Handling and Storage
Storage
Store in a cool, dry, well-ventilated area away from incompatible substances. Poison room locked. Keep containers tightly closed.
Store in a cool, dry, well-ventilated area away from incompatible substances. Poison room locked. Keep containers tightly closed.
Handling
Wash thoroughly after handling. Use only in a well ventilated area. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation.
Wash thoroughly after handling. Use only in a well ventilated area. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation.
Hazards Identification
Inhalation
Dust is irritating to the respiratory tract.
Dust is irritating to the respiratory tract.
Skin
Causes skin irritation.
Causes skin irritation.
Eyes
Dust may cause mechanical irritation.
Dust may cause mechanical irritation.
Ingestion
May be harmful if swallowed. Causes digestive tract irritation.
May be harmful if swallowed. Causes digestive tract irritation.
Hazards
When heated, vapors may form explosive mixtures with air: indoors, outdoors, and sewers explosion hazards.
When heated, vapors may form explosive mixtures with air: indoors, outdoors, and sewers explosion hazards.
EC Risk Phrase
R 23/24/25 33 52/53
R 23/24/25 33 52/53
EC Safety Phrase
S 28 36/37 45 61
S 28 36/37 45 61
UN (DOT)
1661
1661
Exposure Controls/Personal Protection
Personal Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Exposure Effects
Acute poisoning may cause rapid heart rate and rapid breathing. Severe headache, CNS disturbances, and tremor may occur. A high incidence of gynecological disorders and excess frequency of spontaneous abortions have been noted. The fetal liver can n-oxygenate aniline to form phenylhydroxylamine. Fetal effects include higher levels of methemoglobin those found in than the mother. Fetal poisoning may occur. <br>No data were available to assess the potential effects of exposure to aniline during lactation. <br>No information about possible male reproductive effects was found in available references at the time of this review
Acute poisoning may cause rapid heart rate and rapid breathing. Severe headache, CNS disturbances, and tremor may occur. A high incidence of gynecological disorders and excess frequency of spontaneous abortions have been noted. The fetal liver can n-oxygenate aniline to form phenylhydroxylamine. Fetal effects include higher levels of methemoglobin those found in than the mother. Fetal poisoning may occur. <br>No data were available to assess the potential effects of exposure to aniline during lactation. <br>No information about possible male reproductive effects was found in available references at the time of this review
Exposure limit(s)
NIOSH: Potential Occupational Carcinogen.
NIOSH: Potential Occupational Carcinogen.
Fire Fighting Measures
Flash Point
126
126
Autoignition
521
521
Fire Fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. May polymerize explosively when involved in a fire. Contact with metals may evolve flammable hydrogen gas. Containers may explode when heated. Combustible material; may burn but does not ignite readily. Extinguishing media: Cool containers with flooding quantities of water until well after fire is out. In case of fire, use water spray, dry chemical, carbon dioxide, or alcohol-resistant foam.
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. May polymerize explosively when involved in a fire. Contact with metals may evolve flammable hydrogen gas. Containers may explode when heated. Combustible material; may burn but does not ignite readily. Extinguishing media: Cool containers with flooding quantities of water until well after fire is out. In case of fire, use water spray, dry chemical, carbon dioxide, or alcohol-resistant foam.
Upper exp. limit
9.8
9.8
Lower exp. limit
1.5
1.5
Fire Potential
Slightly flammable. Flammable at elevated temperatures - moderate hazard.
Slightly flammable. Flammable at elevated temperatures - moderate hazard.
Accidental Release Measures
Small spills/leaks
Absorb spill with inert material, (e.g., dry sand or earth), then place into a chemical waste container. Avoid runoff into storm sewers and ditches which lead to waterways. Avoid generating dusty conditions. Remove all sources of ignition. Provide ventilation.
Absorb spill with inert material, (e.g., dry sand or earth), then place into a chemical waste container. Avoid runoff into storm sewers and ditches which lead to waterways. Avoid generating dusty conditions. Remove all sources of ignition. Provide ventilation.
Stability and Reactivity
Disposal Code
9
9
Incompatibilities
Acids - acid chlorides - acid anhydrides - chloroformates - strong oxidizing agents.
Acids - acid chlorides - acid anhydrides - chloroformates - strong oxidizing agents.
Stability
Stable under normal temperatures and pressures.
Stable under normal temperatures and pressures.
Decomposition
Nitrogen oxides, carbon monoxide, carbon dioxide, nitrogen.
Nitrogen oxides, carbon monoxide, carbon dioxide, nitrogen.
Combustion Products
Toxic oxides of nitrogen may form in fire.
Toxic oxides of nitrogen may form in fire.
Transport Information
UN Number
1661
1661
Hazard Class
6.1
6.1
Packing Group
II
II
HS Code
2921 42 10
2921 42 10