Supplier Product Identification Physical and Chemical Properties First Aid Measures Handling and Storage Hazards Identification Exposure Controls/Personal Protection Fire Fighting Measures Accidental Release Measures Stability and Reactivity Transport Information
Home > 1,3,4-Thiadiazol-2-amine > 1,3,4-Thiadiazol-2-amine(4005-51-0)

1,3,4-Thiadiazol-2-amine(4005-51-0)

Supplier Product Identification Physical and Chemical Properties First Aid Measures Handling and Storage Hazards Identification Exposure Controls/Personal Protection Fire Fighting Measures Accidental Release Measures Stability and Reactivity Transport Information

Product Identification

Product Name
1,3,4-Thiadiazol-2-amine
Synonyms
1,3,4-Thiadiazol-2-amine
1,3,4-Thiadiazol-2-ylamine
2-Amino-1,3,4-thiadiazole
ATDA
NSC 4728
TF-128
CAS
4005-51-0
Formula
C2H3N3S
Molecular Weight
101.12
EINECS
223-657-7
RTECS
XI3000000
RTECS Class
Mutagen; Reproductive Effector
Beilstein/Gmelin
107135
Beilstein Reference
4-27-00-08053

Physical and Chemical Properties

Appearance
White crystals.
Solubility in water
Very soluble
Melting Point
199 - 201
pKa/pKb
11.13 (pKb)
Partition Coefficient
.71
Usage
Cancer medication.

First Aid Measures

Ingestion
Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water. Wash mouth out with water.
Inhalation
Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid. DO NOT use mouth-to-mouth respiration.
Skin
Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
Eyes
Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.

Handling and Storage

Storage
Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.
Handling
Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Use with adequate ventilation. Wash clothing before reuse.

Hazards Identification

Inhalation
Causes respiratory tract irritation. Can produce delayed pulmonary edema.
Skin
Causes skin irritation.
Eyes
Causes eye irritation. May cause chemical conjunctivitis.
Ingestion
May cause gastrointestinal irritation with nausea, vomiting and diarrhea. The toxicological properties of this substance have not been fully investigated.
EC Risk Phrase
R 22 40 63
EC Safety Phrase
S 22 26 36/37
UN (DOT)
2811

Exposure Controls/Personal Protection

Personal Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Exposure Effects
Effects may be delayed. Reproductive effects have been reported in animals.

Fire Fighting Measures

Fire Fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. To extinguish fire use water spray, dry chemical, carbon dioxide, or appropriate foam.

Accidental Release Measures

Small spills/leaks
Vacuum or sweep up material and place into a suitable disposal container. Clean up spills immediately, using the appropriate protective equipment. Avoid generating dusty conditions. Provide ventilation.

Stability and Reactivity

Stability
Stable at room temperature in closed containers under normal storage and handling conditions.
Incompatibilities
Strong oxidizing agents.
Decomposition
Nitrogen oxides, carbon monoxide, carbon dioxide, sulfur oxides (SOx), including sulfur oxide and sulfur dioxide.

Transport Information

UN Number
2811
Contact More