Supplier Product Identification Physical and Chemical Properties First Aid Measures Handling and Storage Hazards Identification Exposure Controls/Personal Protection Fire Fighting Measures Accidental Release Measures Stability and Reactivity Transport Information
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trans-Diammineplatinum(II) dichloride(14913-33-8)

Supplier Product Identification Physical and Chemical Properties First Aid Measures Handling and Storage Hazards Identification Exposure Controls/Personal Protection Fire Fighting Measures Accidental Release Measures Stability and Reactivity Transport Information

Product Identification

Product Name
trans-Diammineplatinum(II) dichloride
Synonyms
NSC 131558
trans-Diamminedichloroplatinum
trans-Diamminedichloroplatinum(II)
trans-Dichlorodiammineplatinum(II)
trans-Platinum(II)diamminedichloride
CAS
14913-33-8
Formula
Cl2H6N2Pt
Molecular Weight
300.04000000000002
EINECS
238-980-9
RTECS
TP2455000
RTECS Class
Tumorigen; Drug; Mutagen
Beilstein/Gmelin
2520 (G)

Physical and Chemical Properties

Appearance
Deep yellow crystals.
Solubility in water
Slightly soluble
Melting Point
340
Density
3.746 g/cm3
Usage
After undergoing hydrolysis, it reacts with dna to produce both intra and interstrand crosslinks. These crosslinks appear to impair replication and transcription of dna.
Refractive Index
1.706

First Aid Measures

Ingestion
Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
Inhalation
Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Skin
Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
Eyes
Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.

Handling and Storage

Storage
Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.
Handling
Wash thoroughly after handling. Use with adequate ventilation. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation.

Hazards Identification

Inhalation
May cause respiratory tract irritation. The toxicological properties of this substance have not been fully investigated.
Skin
May cause skin irritation.
Eyes
May cause eye irritation.
Ingestion
May cause irritation of the digestive tract. The toxicological properties of this substance have not been fully investigated.
UN (DOT)
3288

Exposure Controls/Personal Protection

Personal Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators
A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use.
Exposure Effects
Possible risk of irreversible effects.
Exposure limit(s)
IDHL: 4 mg/m3

Fire Fighting Measures

Fire Fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Extinguishing media: Use agent most appropriate to extinguish fire. In case of fire use water spray, dry chemical, carbon dioxide, or appropriate foam.
Fire Potential
Non-Combustible

Accidental Release Measures

Small spills/leaks
Clean up spills immediately, using the appropriate protective equipment. Sweep up, then place into a suitable container for disposal. Avoid generating dusty conditions. Provide ventilation.

Stability and Reactivity

Incompatibilities
Oxidizing agents.
Stability
Stable under normal temperatures and pressures.
Decomposition
Hydrogen chloride, nitrogen oxides, irritating and toxic fumes and gases, nitrogen.
Combustion Products
Toxic gases and vapors (such as chlorine) may be released when chlorine-containing soluble platinum salts decompose.

Transport Information

UN Number
3288
Hazard Class
6.1
Packing Group
I; II; III
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