Supplier Product Identification Physical and Chemical Properties First Aid Measures Exposure Controls/Personal Protection Fire Fighting Measures Accidental Release Measures Stability and Reactivity Hazards Identification
Home > 17a-Ethynyl-1,3,5(10)-estratriene-3,17b-diol 3-cyclopentyl ether > 17a-Ethynyl-1,3,5(10)-estratriene-3,17b-diol 3-cyclopentyl ether(152-43-2)

17a-Ethynyl-1,3,5(10)-estratriene-3,17b-diol 3-cyclopentyl ether(152-43-2)

Supplier Product Identification Physical and Chemical Properties First Aid Measures Exposure Controls/Personal Protection Fire Fighting Measures Accidental Release Measures Stability and Reactivity Hazards Identification

Product Identification

Product Name
17a-Ethynyl-1,3,5(10)-estratriene-3,17b-diol 3-cyclopentyl ether
Synonyms
17a-Ethynyl-1,3,5(10)-estratriene-3,17b-diol 3-cyclopentyl ether
17a-Ethynylestradiol 3-cyclopentyl ether17a-ethynyl-1,3,5(10)-estratriene-3,17b-diol 3-cyclopentyl ether
19-Nor-17a-pregna-1,3,5(10)-trien-20-yn-17-ol, 3-(cyclopentyloxy)-
3-(Cyclopentyloxy)-19-nor-17a-pregna-1,3,5(10)-trien-20-yn-17-ol

3-Cyclopentyloxy-17a-ethynyl-1,3,5(10)-estratrien-17-ol
Ethynylestradiol-3-cyclopentyl ether
CAS
152-43-2
Formula
C25H32O2
Molecular Weight
364.53
EINECS
205-803-1
RTECS
RC8948000
RTECS Class
Drug; Reproductive Effector; Human Data; Hormone
Merck
12,8239
Beilstein/Gmelin
2013312
Beilstein Reference
5-06

Physical and Chemical Properties

Solubility in water
Insoluble
Melting Point
107 - 108
Vapor Pressure
6E-11 (25 C)
pKa/pKb
13.10 (pKa)
Partition Coefficient
5.4
Heat Of Vaporization
81.3 kJ/mol
Usage
Used to treat symptoms of menopause, such as hot flashes. Also used to treat breast and prostate cancer.

First Aid Measures

Ingestion
If swallowed, wash out mouth with water provided person is conscious. Call a physician.
Inhalation
If inhaled, remove to fresh air. If breathing becomes difficult, call a physician.
Skin
In case of skin contact, flush with copious amounts of water for at least 15 minutes. Remove contaminated clothing and shoes. Call a physician.
Eyes
In case of contact with eyes, flush with copious amounts of water for at least 15 minutes. Assure adequate flushing by separating the eyelids with fingers. Call a physician.

Exposure Controls/Personal Protection

Personal Protection
Wear appropriate government approved respirator, chemical-resistant gloves, safety goggles, other protective clothing.
Exposure Effects
Toxic. May cause cancer. Harmful by inhalation, in contact with skin and if swallowed. May cause harm to the unborn child. Reproductive hazard. Target organ(s): Liver. Blood.

Fire Fighting Measures

Flash Point
219
Fire Fighting
Extinguish using Water spray. Carbon dioxide, dry chemical powder, or appropriate foam. Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.

Accidental Release Measures

Small spills/leaks
Sweep up, place in a bag and hold for waste disposal. Ventilate area and wash spill site after material pickup is complete.

Stability and Reactivity

Stability
Stable at normal temperatures and pressures.
Incompatibilities
Strong oxidizing agents.
Decomposition
Carbon monoxide, Carbon dioxide.

Hazards Identification

Hazards
Emits toxic fumes under fire conditions.
EC Risk Phrase
45 61 20/21/22
EC Safety Phrase
53 22 36/37/39 45
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