Supplier Product Identification Physical and Chemical Properties First Aid Measures Handling and Storage Hazards Identification Exposure Controls/Personal Protection Fire Fighting Measures Accidental Release Measures Stability and Reactivity
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Genistein(446-72-0)

Supplier Product Identification Physical and Chemical Properties First Aid Measures Handling and Storage Hazards Identification Exposure Controls/Personal Protection Fire Fighting Measures Accidental Release Measures Stability and Reactivity

Product Identification

Product Name
Genistein
Synonyms
4',5,7-Trihydroxyisoflavone
4H-1-Benzopyran-4-one, 5,7-dihydroxy-3-(4-hydroxyphenyl)-
5,7,4'-Trihydroxyisoflavone
Baichanin A
C.I. 75610
Sophoricol
CAS
446-72-0
Formula
C15H10O5
Molecular Weight
270.24
EINECS
207-174-9
RTECS
NR2392000
RTECS Class
Tumorigen; Drug; Mutagen; Reproductive Effector
Merck
13,4402
Beilstein/Gmelin
263823
Beilstein Reference
5-18-04-00594

Physical and Chemical Properties

Appearance
odorless yellow-white powder
Solubility in water
Insoluble
Melting Point
297-298
pKa/pKb
7.08 (pKa)
Partition Coefficient
2.84
Usage
Chemical probe to explore signal transduction pathways.

First Aid Measures

Ingestion
Get medical aid. Wash mouth out with water.
Inhalation
Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Skin
Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes.
Eyes
Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.

Handling and Storage

Storage
Store in a tightly closed container. Refrigerator (approx 4 C).
Handling
Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes.

Hazards Identification

Ingestion
May cause irritation of the digestive tract. May be harmful if swallowed.
Inhalation
May cause respiratory tract irritation. May be harmful if inhaled.
Skin
May cause skin irritation. May be harmful if absorbed through the skin. May cause allergic dermatitis called nickel itch. Symptoms may include burns and ulceration of skin.
Eyes
May cause eye irritation.
EC Risk Phrase
R 36/37/38
EC Safety Phrase
S 26 36

Exposure Controls/Personal Protection

Personal Protection
Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.

Fire Fighting Measures

Fire Fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. To extinguish fire use water spray, dry chemical, carbon dioxide, or chemical foam.

Accidental Release Measures

Small spills/leaks
Vacuum or sweep up material and place into a suitable disposal container.

Stability and Reactivity

Stability
No data.
Incompatibilities
Strong oxidizing agents.
Decomposition
Carbon monoxide, carbon dioxide.
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