Supplier Product Identification Physical and Chemical Properties First Aid Measures Handling and Storage Hazards Identification Exposure Controls/Personal Protection Fire Fighting Measures Accidental Release Measures Stability and Reactivity
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Provitamine D2(57-87-4)

Supplier Product Identification Physical and Chemical Properties First Aid Measures Handling and Storage Hazards Identification Exposure Controls/Personal Protection Fire Fighting Measures Accidental Release Measures Stability and Reactivity

Product Identification

Product Name
Provitamine D2
Synonyms
delta-5,7,22-Ergostatrien-3beta-ol
Ergosta-5,7,22-trien-3-beta-ol
Ergosta-5:6,7:8,22:23-trien-3-ol
Ergosterin
Provitamin D
Provitamin D2
CAS
57-87-4
Formula
C28H44O
Molecular Weight
396.66
EINECS
200-352-7
Merck
12,3701
Beilstein/Gmelin
2062413

Physical and Chemical Properties

Appearance
White powder.
Solubility in water
Insoluble
Melting Point
162
Boiling Point
502
Vapor Pressure
4E-12 (25 C)
Density
1.04 g/cm3 (20 C)
Partition Coefficient
9.34
Heat Of Vaporization
88.7 kJ/mol
Usage
Chemical intermediate for vitamin d2.

First Aid Measures

Ingestion
If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid.
Inhalation
Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid if cough or other symptoms appear.
Skin
Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Get medical aid if irritation develops or persists.
Eyes
Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.

Handling and Storage

Storage
Keep container closed when not in use. Store in a cool, dry, well-ventilated area away from incompatible substances.
Handling
Wash thoroughly after handling. Use only in a well ventilated area. Avoid contact with eyes, skin, and clothing. Avoid ingestion and inhalation.

Hazards Identification

Inhalation
Inhalation of dust may cause respiratory tract irritation.
Skin
May cause skin irritation.
Eyes
Dust may cause mechanical irritation.
Ingestion
May cause gastrointestinal irritation with nausea, vomiting and diarrhea. May cause headache, nausea, fatigue, and dizziness. Ingestion of large amounts of vitamin D may result in hypercalcemia.

Exposure Controls/Personal Protection

Personal Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Exposure Effects
Prolonged hypercalcemia may result in a deposition of calcium salts in the soft tissues, most significantly the kidney.

Fire Fighting Measures

Flash Point
216
Fire Fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. To extinguish fire, use water fog, dry chemical, carbon dioxide, or regular foam. Use agent most appropriate to extinguish fire.

Accidental Release Measures

Small spills/leaks
Clean up spills immediately, using the appropriate protective equipment. Sweep up, then place into a suitable container for disposal. Avoid generating dusty conditions. Provide ventilation.

Stability and Reactivity

Stability
Stable under normal temperatures and pressures. Substance undergoes color change upon exposure to light and air.
Incompatibilities
Strong oxidizing agents, acids.
Decomposition
Carbon monoxide, carbon dioxide.
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