Supplier Product Identification Physical and Chemical Properties First Aid Measures Handling and Storage Hazards Identification Exposure Controls/Personal Protection Fire Fighting Measures Accidental Release Measures Stability and Reactivity
Home > 3-(3,4-Dihydroxyphenyl)-2-hydrazinyl-2-methyl-propanoic acid > 3-(3,4-Dihydroxyphenyl)-2-hydrazinyl-2-methyl-propanoic acid(28860-95-9)

3-(3,4-Dihydroxyphenyl)-2-hydrazinyl-2-methyl-propanoic acid(28860-95-9)

Supplier Product Identification Physical and Chemical Properties First Aid Measures Handling and Storage Hazards Identification Exposure Controls/Personal Protection Fire Fighting Measures Accidental Release Measures Stability and Reactivity

Product Identification

Product Name
3-(3,4-Dihydroxyphenyl)-2-hydrazinyl-2-methyl-propanoic acid
Synonyms
Hydrazino-a-methyldopa
L-3-(3,4-Dihydroxyphenyl)-2-methyl-2-hydrazinopropionic acid
L-a-Hydrazino-a-methyl-b-(3,4-dihydroxyphenyl)propionic acid
L-alpha-Methyldopahydrazine
N-Aminomethyldopa
S-(-)-a-Hydrazino-3,4-dihydroxy-2-methylbenzenepropanoic acid
CAS
28860-95-9
Formula
C10H16N2O5
Molecular Weight
244.25
EINECS
249-271-9
RTECS
MW5298000
RTECS Class
Drug; Mutagen; Reproductive Effector
Merck
12,1843
Beilstein/Gmelin
657532
Beilstein Reference
5-15

Physical and Chemical Properties

Solubility in water
Very soluble
Melting Point
206 - 208
Boiling Point
419
Vapor Pressure
5E-12 (25 C)
pKa/pKb
3.40 (pKa)
Partition Coefficient
.46
Heat Of Vaporization
84.6 kJ/mol
Usage
Peripheral inhibitor ofl-aromatic amino acid decarboxylase. When administered simultaneously withl-dopa, it prevents extracerebral conversion to dopamine.

First Aid Measures

Ingestion
If swallowed, wash out mouth with water provided person is conscious. Call a physician.
Inhalation
If inhaled, remove to fresh air. If not breathing give artificial respiration. If breathing is difficult, give oxygen.
Skin
In case of contact, immediately wash skin with soap and copious amounts of water.
Eyes
In case of contact, immediately flush eyes with copious amounts of water for at least 15 minutes.

Handling and Storage

Storage
Keep tightly closed. Store in a cool dry place. Store at -20 C

Hazards Identification

Inhalation
Material may be irritating to mucous membranes and upper respiratory tract.
Skin
May cause skin irritation.
Eyes
May cause eye irritation.
Hazards
Emits toxic fumes under fire conditions.

Exposure Controls/Personal Protection

Personal Protection
Compatible chemical-resistant gloves. Chemical safety goggles.
Respirators
Government approved respirator.
Exposure Effects
Avoid contact and inhalation.

Fire Fighting Measures

Fire Fighting
Extinguish using Water spray. Carbon dioxide, dry chemical powder, or appropriate foam. Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.

Accidental Release Measures

Small spills/leaks
Sweep up, place in a bag and hold for waste disposal. Avoid raising dust. Ventilate area and wash spill site after material pickup is complete.

Stability and Reactivity

Incompatibilities
Strong oxidizing agents.
Decomposition
Carbon monoxide, Carbon dioxide, Nitrogen oxides.
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