Supplier Product Identification Physical and Chemical Properties First Aid Measures Hazards Identification Exposure Controls/Personal Protection Fire Fighting Measures Accidental Release Measures Stability and Reactivity
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1(3-chloro-2-hydroxypropyl)-2-methyl-5-nitro imidazole(16773-42-5)

Supplier Product Identification Physical and Chemical Properties First Aid Measures Hazards Identification Exposure Controls/Personal Protection Fire Fighting Measures Accidental Release Measures Stability and Reactivity

Product Identification

Product Name
1(3-chloro-2-hydroxypropyl)-2-methyl-5-nitro imidazole
Synonyms
(+/-)-Tiberal
1-(3-Chloro-2-hydroxypropyl)-2-methyl-5-nitroimidazole
1-Chloro-3-(2-methyl-5-nitroimidazol-1-yl)propan-2-ol
a-(Chloromethyl)-2-methyl-5-nitro-1H-imidazole-1-ethanol
CAS
16773-42-5
Formula
C7H10ClN3O3
Molecular Weight
219.63
EINECS
240-826-0
RTECS
NI5460000
RTECS Class
Drug; Mutagen; Reproductive Effector
Merck
12,7000
Beilstein/Gmelin
614299
Beilstein Reference
5-23-05-00072

Physical and Chemical Properties

Solubility in water
Slightly soluble
Melting Point
85.4
Boiling Point
443
Vapor Pressure
1E-8 (25 C)
pKa/pKb
11.28 (pKb)
Heat Of Vaporization
73.9 kJ/mol
Usage
An antiprotozoal compound for treatment of trichomonas vaginalis infection.

First Aid Measures

Ingestion
If swallowed, wash out mouth with water provided person is conscious. Call a physician.
Inhalation
If inhaled, remove to fresh air. If breathing becomes difficult, call a physician.
Skin
In case of skin contact, flush with copious amounts of water for at least 15 minutes. Remove contaminated clothing and shoes. Call a physician.
Eyes
In case of contact with eyes, flush with copious amounts of water for at least 15 minutes. Assure adequate flushing by separating the eyelids with fingers. Call a physician.

Hazards Identification

Inhalation
May be harmful if inhaled.
Skin
May be harmful if absorbed through the skin.
Ingestion
Harmful if swallowed.
Hazards
Emits toxic fumes under fire conditions.
EC Risk Phrase
22
EC Safety Phrase
36

Exposure Controls/Personal Protection

Personal Protection
Wear appropriate government approved respirator, chemical-resistant gloves, safety goggles, other protective clothing.
Exposure Effects
Harmful. Harmful if swallowed. Avoid contact and inhalation.

Fire Fighting Measures

Flash Point
222
Fire Fighting
Extinguish using Carbon dioxide, dry chemical powder, or appropriate foam. Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.

Accidental Release Measures

Small spills/leaks
Sweep up, place in a bag and hold for waste disposal. Avoid raising dust. Ventilate area and wash spill site after material pickup is complete.

Stability and Reactivity

Stability
Stable at normal temperatures and pressures.
Decomposition
Carbon monoxide, Carbon dioxide, Nitrogen oxides, Hydrogen chloride gas.
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