Home > 5-Ethyl-5-(1-methylbutyl)barbituric acid > 5-Ethyl-5-(1-methylbutyl)barbituric acid(76-74-4)
5-Ethyl-5-(1-methylbutyl)barbituric acid(76-74-4)
Product Identification
Physical and Chemical Properties
First Aid Measures
Handling and Storage
Hazards Identification
Exposure Controls/Personal Protection
Fire Fighting Measures
Accidental Release Measures
Stability and Reactivity
Product Identification
Product Name
5-Ethyl-5-(1-methylbutyl)barbituric acid
5-Ethyl-5-(1-methylbutyl)barbituric acid
Synonyms
5-Ethyl-5-(1-methylbutyl)barbituric acid
5-Ethyl-5-(1-methylbutyl)malonylurea
5-Ethyl-5-(sec-pentyl)barbituric acid
Barpental
Ethaminal
Mebubarbital
5-Ethyl-5-(1-methylbutyl)barbituric acid
5-Ethyl-5-(1-methylbutyl)malonylurea
5-Ethyl-5-(sec-pentyl)barbituric acid
Barpental
Ethaminal
Mebubarbital
CAS
76-74-4
76-74-4
Formula
C11H18N2O3
C11H18N2O3
Molecular Weight
226.28
226.28
EINECS
200-983-8
200-983-8
RTECS
CQ5775000
CQ5775000
RTECS Class
Drug; Reproductive Effector; Human Data
Drug; Reproductive Effector; Human Data
Merck
12,7272
12,7272
Beilstein/Gmelin
87067
87067
Beilstein Reference
5-24-09-00168
5-24-09-00168
Physical and Chemical Properties
Appearance
White to practically white, fine, powder. Practically odorless.
White to practically white, fine, powder. Practically odorless.
Solubility in water
Insoluble
Insoluble
Melting Point
129-130
129-130
Boiling Point
506
506
pKa/pKb
7.88 (pKa)
7.88 (pKa)
Partition Coefficient
2.1
2.1
Heat Of Vaporization
Usage
This is a drug of abuse.
This is a drug of abuse.
First Aid Measures
Ingestion
Seek medical attention. If individual is drowsy or unconscious, do not give anything by mouth; place individual on the left side with the head down. Contact a physician, medical facility, or poison control center for advice about whether to induce vomiting. If possible, do not leave individual unattended.
Seek medical attention. If individual is drowsy or unconscious, do not give anything by mouth; place individual on the left side with the head down. Contact a physician, medical facility, or poison control center for advice about whether to induce vomiting. If possible, do not leave individual unattended.
Inhalation
If symptoms develop, move individual away from exposure and into fresh air. If symptoms persist, seek medical attention. If breathing is difficult, administer oxygen. Keep person warm and quiet; seek immediate medical attention.
If symptoms develop, move individual away from exposure and into fresh air. If symptoms persist, seek medical attention. If breathing is difficult, administer oxygen. Keep person warm and quiet; seek immediate medical attention.
Skin
Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes.
Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes.
Eyes
If symptoms develop, immediately move individual away from exposure and into fresh air. Flush eyes gently with water for at least 15 minutes while holding eyelids apart; seek immediate medical attention.
If symptoms develop, immediately move individual away from exposure and into fresh air. Flush eyes gently with water for at least 15 minutes while holding eyelids apart; seek immediate medical attention.
Handling and Storage
Storage
Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.
Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.
Handling
All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.
All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.
Hazards Identification
Inhalation
Respiratory arrest may occur following severe intoxication. Aspiration pneumonia has been reported, in barbiturate ingestions, following vomiting of gastric contents.
Respiratory arrest may occur following severe intoxication. Aspiration pneumonia has been reported, in barbiturate ingestions, following vomiting of gastric contents.
Skin
Erythematous or hemorrhagic blisters (barb - burns) may occasionally occur on the hands, buttocks, in between the knees, and at any pressure point.
Erythematous or hemorrhagic blisters (barb - burns) may occasionally occur on the hands, buttocks, in between the knees, and at any pressure point.
Ingestion
Respiratory arrest may occur following severe intoxication. Aspiration pneumonia has been reported, in barbiturate ingestions, following vomiting of gastric contents.
Respiratory arrest may occur following severe intoxication. Aspiration pneumonia has been reported, in barbiturate ingestions, following vomiting of gastric contents.
Exposure Controls/Personal Protection
Personal Protection
Chemical splash goggles in compliance with OSHA regulations are advised; however, OSHA regulations also permit other type safety glasses. Whre chemical resistant gloves. To prevent repeated or prolonged skin contact, wear impervious clothing and boots.
Chemical splash goggles in compliance with OSHA regulations are advised; however, OSHA regulations also permit other type safety glasses. Whre chemical resistant gloves. To prevent repeated or prolonged skin contact, wear impervious clothing and boots.
Respirators
Use NIOSH/MSHA approved respirator appropriate for exposure of concern.
Use NIOSH/MSHA approved respirator appropriate for exposure of concern.
Exposure Effects
CNS findings range from drowsiness to deep coma. Seizures are not expected, except upon withdrawal from barbiturate dependence.
CNS findings range from drowsiness to deep coma. Seizures are not expected, except upon withdrawal from barbiturate dependence.
Fire Fighting Measures
Fire Fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Use agent most appropriate to extinguish fire.
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Use agent most appropriate to extinguish fire.
Accidental Release Measures
Small spills/leaks
Evacuate area and ventilate. Wear protective equipment. If required, use an inert absrobent. Sweep up and place in an appropriate container for disposal. Wash contaminated surfaces.
Evacuate area and ventilate. Wear protective equipment. If required, use an inert absrobent. Sweep up and place in an appropriate container for disposal. Wash contaminated surfaces.
Stability and Reactivity
Stability
Aq solution of pentobarbital sodium are not Pentobarbital sodium sensitive to air and moisture pentobarbital sodium alkaline solution decomp on storage and heating.
Aq solution of pentobarbital sodium are not Pentobarbital sodium sensitive to air and moisture pentobarbital sodium alkaline solution decomp on storage and heating.
Incompatibilities
Strong oxidizing agents.
Strong oxidizing agents.