Supplier Product Identification Physical and Chemical Properties First Aid Measures Handling and Storage Hazards Identification Exposure Controls/Personal Protection Fire Fighting Measures Accidental Release Measures Stability and Reactivity
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Gliclazide(21187-98-4)

Supplier Product Identification Physical and Chemical Properties First Aid Measures Handling and Storage Hazards Identification Exposure Controls/Personal Protection Fire Fighting Measures Accidental Release Measures Stability and Reactivity

Product Identification

Product Name
Gliclazide
Synonyms
1-(3,3a,4,5,6,6a-Hexahydro-1H-cyclopenta[c]pyrrol-2-yl)-3-(4-methylphenyl)sulfonylurea
1-(Hexahydrocyclopenta[c]pyrrol-2(1H)-yl)-3-(p-tolylsulfonyl)urea
N-(4-Methylbenzenesulfonyl)-N'-[3-azabicyclo(3,3,0)oct-3-yl]urea
CAS
21187-98-4
Formula
C15H21N3O3S
Molecular Weight
323.42
EINECS
244-260-5
RTECS
YT4500000
RTECS Class
Drug; Reproductive Effector; Human Data
Merck
12,4448
Beilstein/Gmelin
1657836
Beilstein Reference
6-20

Physical and Chemical Properties

Solubility in water
Slightly soluble
Melting Point
180 - 182
Density
1.319 g/cm3
pKa/pKb
7.82 (pKb)
Usage
Medicine used to help control blood sugar levels in people with type 2 diabetes.

First Aid Measures

Ingestion
If swallowed, wash out mouth with water provided person is conscious. Call a physician.
Inhalation
If inhaled, remove to fresh air. If breathing becomes difficult, call a physician.
Skin
In case of contact, immediately wash skin with soap and copious amounts of water.
Eyes
In case of contact with eyes, flush with copious amounts of water for at least 15 minutes. Assure adequate flushing by separating the eyelids with fingers. Call a physician.

Handling and Storage

Storage
Keep tightly closed.

Hazards Identification

Ingestion
May be harmful if swallowed.
Inhalation
May be harmful if inhaled. Material may be irritating to mucous membranes and upper respiratory tract.
Skin
May cause skin irritation. May be harmful if absorbed through the skin.
Eyes
May cause eye irritation.
Hazards
Emits toxic fumes under fire conditions.

Exposure Controls/Personal Protection

Personal Protection
Protective gloves. Chemical safety goggles.
Respirators
Wear dust mask.

Fire Fighting Measures

Fire Fighting
Extinguish using Water spray. Carbon dioxide, dry chemical powder, or appropriate foam. Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.

Accidental Release Measures

Small spills/leaks
Sweep up, place in a bag and hold for waste disposal. Avoid raising dust. Ventilate area and wash spill site after material pickup is complete.

Stability and Reactivity

Incompatibilities
Acids, Bases, Strong oxidizing agents.
Stability
Stable at normal temperatures and pressures. Heat.
Decomposition
Carbon monoxide, Carbon dioxide, Nitrogen oxides, Sulfur oxides.
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