Supplier Product Identification Physical and Chemical Properties First Aid Measures Handling and Storage Hazards Identification Exposure Controls/Personal Protection Fire Fighting Measures Accidental Release Measures Stability and Reactivity
Home > (9alpha,13alpha,14alpha)-7,8-Didehydro-4-hydroxy-3,7-dimethoxy-17-methylmorphinan-6-one > (9alpha,13alpha,14alpha)-7,8-Didehydro-4-hydroxy-3,7-dimethoxy-17-methylmorphinan-6-one(115-53-7)

(9alpha,13alpha,14alpha)-7,8-Didehydro-4-hydroxy-3,7-dimethoxy-17-methylmorphinan-6-one(115-53-7)

Supplier Product Identification Physical and Chemical Properties First Aid Measures Handling and Storage Hazards Identification Exposure Controls/Personal Protection Fire Fighting Measures Accidental Release Measures Stability and Reactivity

Product Identification

Product Name
(9alpha,13alpha,14alpha)-7,8-Didehydro-4-hydroxy-3,7-dimethoxy-17-methylmorphinan-6-one
Synonyms
(9a,13a,14a)-7,8-didehydro-4-hydroxy-3,7-dimethoxy-17-methylmorphinan-6-one
Cucoline
CAS
115-53-7
Formula
C19H23NO4
Molecular Weight
329.4
EINECS
204-094-6
RTECS
QD2170000
RTECS Class
Drug
Merck
12,8692
Beilstein/Gmelin
95280
Beilstein Reference
5-21-13-00516

Physical and Chemical Properties

Appearance
A toxic crystalline alkaloid from the root of Sinomenium acutum, structurally related to thebaine.
Solubility in water
Insoluble
Melting Point
219 - 221
Boiling Point
513
Vapor Pressure
3E-11 (25 C)
pKa/pKb
9.71 (pKa)
Heat Of Vaporization
81.5 kJ/mol
Usage
Anti-inflammatory.
Refractive Index
 

First Aid Measures

Ingestion
If swallowed, wash out mouth with water provided person is conscious. Call a physician.
Inhalation
If inhaled, remove to fresh air. If breathing becomes difficult, call a physician.
Skin
In case of skin contact, flush with copious amounts of water for at least 15 minutes. Remove contaminated clothing and shoes. Call a physician.
Eyes
In case of contact with eyes, flush with copious amounts of water for at least 15 minutes. Assure adequate flushing by separating the eyelids with fingers. Call a physician.

Handling and Storage

Storage
Keep tightly closed. Store in a cool dry place.

Hazards Identification

Inhalation
Material is irritating to mucous membranes and upper respiratory tract.
Hazards
Emits toxic fumes under fire conditions.
EC Risk Phrase
45 46 23/24/25 36/37/38
EC Safety Phrase
53 22 26 36/37/39 45

Exposure Controls/Personal Protection

Personal Protection
Compatible chemical-resistant gloves. Chemical safety goggles.
Respirators
Government approved respirator.
Exposure Effects
May cause cancer. May cause heritable genetic damage. Toxic by inhalation, in contact with skin and if swallowed. Irritating to eyes, respiratory system and skin. Target organ(s): Liver. Kidneys.

Fire Fighting Measures

Flash Point
264
Fire Fighting
Extinguish using Water spray. Carbon dioxide, dry chemical powder, or appropriate foam. Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.

Accidental Release Measures

Small spills/leaks
Sweep up, place in a bag and hold for waste disposal. Avoid raising dust. Ventilate area and wash spill site after material pickup is complete.

Stability and Reactivity

Incompatibilities
Strong oxidizing agents.
Decomposition
Carbon monoxide, Carbon dioxide, Nitrogen oxides, Hydrogen chloride gas, Phosgene gas.
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