Supplier Product Identification Physical and Chemical Properties First Aid Measures Handling and Storage Exposure Controls/Personal Protection Fire Fighting Measures Accidental Release Measures Stability and Reactivity Hazards Identification
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N-((4-Aminophenyl)sulfonyl)acetamide(144-80-9)

Supplier Product Identification Physical and Chemical Properties First Aid Measures Handling and Storage Exposure Controls/Personal Protection Fire Fighting Measures Accidental Release Measures Stability and Reactivity Hazards Identification

Product Identification

Product Name
N-((4-Aminophenyl)sulfonyl)acetamide
Synonyms
Acetosulfamin
N-[(4-Aminophenyl)sulfonyl]acetamide
N-Acetylsulfanilamide
p-Aminobenzenesulfonacetamide
Sulfacetamide
Urosulfon
CAS
144-80-9
Formula
C8H10N2O3S
Molecular Weight
214.25
EINECS
205-640-6
RTECS
AC8450000
RTECS Class
Mutagen; Reproductive Effector
Merck
12,9067
Beilstein/Gmelin
981718
Beilstein Reference
4-14-00-02662

Physical and Chemical Properties

Appearance
White powder.
Solubility in water
Insoluble
Melting Point
172 - 174
Boiling Point
475
Vapor Pressure
3E-9 (25 C)
Density
1.37 g/cm3
pKa/pKb
10.07 (pKb)
Partition Coefficient
3.05
Heat Of Vaporization
73.9 kJ/mol
Usage
A sulfonamide antibiotic. It may also have anti-inflammatory properties .
Refractive Index
1.5611 (176 C)

First Aid Measures

Ingestion
DO NOT INDUCE VOMITING. If the victim is conscious and not convulsing, give 1 or 2 glasses of water to dilute the chemical and IMMEDIATELY call a hospital or poison control center. Be prepared to transport the victim to a hospital if advised by a physician.
Inhalation
IMMEDIATELY leave the contaminated area; take deep breaths of fresh air. If symptoms (such as wheezing, coughing, shortness of breath, or burning in the mouth, throat, or chest) develop, call a physician and be prepared to transport the victim to a hospital. Provide proper respiratory protection to rescuers entering an unknown atmosphere. Whenever possible, Self-Contained Breathing Apparatus (SCBA) should be used.
Skin
IMMEDIATELY flood affected skin with water while removing and isolating all contaminated clothing. Gently wash all affected skin areas thoroughly with soap and water. If symptoms such as redness or irritation develop, IMMEDIATELY call a physician and be prepared to transport the victim to a hospital for treatment.
Eyes
First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.

Handling and Storage

Storage
Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.
Handling
All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.

Exposure Controls/Personal Protection

Personal Protection
Chemical splash goggles in compliance with OSHA regulations are advised; however, OSHA regulations also permit other type safety glasses. Whre chemical resistant gloves. To prevent repeated or prolonged skin contact, wear impervious clothing and boots.
Respirators
Wear a NIOSH-approved half face respirator equipped with an organic vapor/acid gas cartridge (specific for organic vapors, HCl, acid gas and SO2) with a dust/mist filter.
Exposure Effects
The toxicological properties of this material have not been investigated.

Fire Fighting Measures

Flash Point
241
Fire Fighting
Fires involving this material can be controlled with a dry chemical, carbon dioxide or Halon extinguisher.
Fire Potential
This material is probably combustible.

Accidental Release Measures

Small spills/leaks
Should a spill occur while you are handling this chemical, FIRST REMOVE ALL SOURCES OF IGNITION, then you should dampen the solid spill material with 60-70% ethanol and transfer the dampened material to a suitable container. Use absorbent paper dampened with 60-70% ethanol to pick up any remaining material. Seal the absorbent paper, and any of your clothes, which may be contaminated, in a vapor-tight plastic bag for eventual disposal. Solvent wash all contaminated surfaces with 60-70% ethanol followed by washing with a soap and water solution. Do not reenter the contaminated area until the Safety Officer (or other responsible person) has verified that the area has been properly cleaned.

Stability and Reactivity

Stability
No data.
Incompatibilities
Organic amides/imides react with azo and diazo compounds to generate toxic gases Flammable gases are formed by the reaction of organic amides/imides with strong reducing agents Can react as acids.

Hazards Identification

EC Risk Phrase
R 40
EC Safety Phrase
S 22 36/37
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