Supplier Product Identification Physical and Chemical Properties First Aid Measures Handling and Storage Exposure Controls/Personal Protection Fire Fighting Measures Accidental Release Measures
Home > 1-[3-(2-Dimethylaminoethyl)-1H-indol-5-yl]-N-methyl-methanesulfonamide > 1-[3-(2-Dimethylaminoethyl)-1H-indol-5-yl]-N-methyl-methanesulfonamide(103628-46-2)

1-[3-(2-Dimethylaminoethyl)-1H-indol-5-yl]-N-methyl-methanesulfonamide(103628-46-2)

Supplier Product Identification Physical and Chemical Properties First Aid Measures Handling and Storage Exposure Controls/Personal Protection Fire Fighting Measures Accidental Release Measures

Product Identification

Product Name
1-[3-(2-Dimethylaminoethyl)-1H-indol-5-yl]-N-methyl-methanesulfonamide
Synonyms
3-(2-(Dimethylamino)ethyl)-N-methyl-1H-indole-5-methanesulfonamide
GR-43175
GR-43175X
Imigran
Imitrex
CAS
103628-46-2
Formula
C14H21N3O2S
Molecular Weight
295.41000000000003
RTECS
NL9482200
Merck
12,9172
Beilstein/Gmelin
6930870

Physical and Chemical Properties

Appearance
Distributed as a 5 - 20% aqueous solution.
Solubility in water
Soluble
Melting Point
169 - 171
Boiling Point
498
Vapor Pressure
4.8E-10 (25 C)
Density
1.243 g/cm3 (20 C)
pKa/pKb
11.31 (pKa)
Partition Coefficient
-2.3
Heat Of Vaporization
76.6 kJ/mol
Usage
A triptan drug including a sulfonamide group.

First Aid Measures

Ingestion
Never attempt to induce vomiting. Do not attempt to give any solid or liquid by mouth if the exposed subject is unconscious or semi-conscious. Wash out the mouth with water. If the exposed subject is fully conscious, give plenty of water to drink. Obtain medical attention.
Inhalation
Physical form suggests that risk of inhalation exposure is negligible.
Skin
Using appropriate personal protective equipment, remove contaminated clothing and flush exposed area with large amounts of water. Obtain medical attention if skin reaction occurs, which may be immediate or delayed.
Eyes
Wash immediately with clean and gently flowing water. Continue for at least 15 minutes. Obtain medical attention.

Handling and Storage

Storage
No storage requirements necessary for occupational hazards. Follow product information storage instructions to maintain efficacy.

Exposure Controls/Personal Protection

Personal Protection
Protective gloves and clothing. Chemical safety goggles.
Exposure Effects
Medical treatment in cases of overexposure should be treated as an overdose of a 5-hydroxytryptamine agonist. Treat according to locally accepted protocols. For additional guidance, refer to the current prescribing information or to the local poison control information centre.

Fire Fighting Measures

Fire Fighting
For single units (packages): No special requirements needed. For larger amounts (multiple packages/pallets) of product: Since toxic, corrosive or flammable vapors might be evolved from fires involving this product and associated packaging, self contained breathing apparatus and full protective equipment are recommended for firefighters. If possible, contain and collect firefighting water for later disposal.
Fire Potential
Product is non combustable.

Accidental Release Measures

Small spills/leaks
Collect and place it in a suitable, properly labeled container for recovery or disposal.
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