Supplier Product Identification Physical and Chemical Properties First Aid Measures Handling and Storage Hazards Identification Exposure Controls/Personal Protection Fire Fighting Measures Accidental Release Measures Stability and Reactivity
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Ethyl (3alpha,16alpha)-eburnamenine-14-carboxylate(42971-09-5)

Supplier Product Identification Physical and Chemical Properties First Aid Measures Handling and Storage Hazards Identification Exposure Controls/Personal Protection Fire Fighting Measures Accidental Release Measures Stability and Reactivity

Product Identification

Product Name
Ethyl (3alpha,16alpha)-eburnamenine-14-carboxylate
Synonyms
(3a, 16a)-Eburnamenine-14-carboxylic acid ethyl ester
Cavinton
Eburnamenine-14-carboxylic acid ethyl ester
Ethyl apovincaminate
CAS
42971-09-5
Formula
C22H26N2O2
Molecular Weight
350.46
EINECS
256-028-0
RTECS
JW4792000
RTECS Class
Drug; Reproductive Effector
Merck
12,10128
Beilstein/Gmelin
900803
Beilstein Reference
6-25

Physical and Chemical Properties

Appearance
White powder.
Solubility in water
Insoluble
Melting Point
147 - 153
Boiling Point
480
Vapor Pressure
2E-9 (25 C)
Density
1.27 g/cm3
pKa/pKb
5.95 (pKb)
Heat Of Vaporization
74.5 kJ/mol
Usage
Ca - calmodulin-dependent phosphodiesterase i (pde1) inhibitor.

First Aid Measures

Ingestion
If swallowed, wash out mouth with water provided person is conscious. Call a physician.
Inhalation
If inhaled, remove to fresh air. If not breathing give artificial respiration. If breathing is difficult, give oxygen.
Skin
In case of skin contact, flush with copious amounts of water for at least 15 minutes. Remove contaminated clothing and shoes. Call a physician.
Eyes
In case of contact with eyes, flush with copious amounts of water for at least 15 minutes. Assure adequate flushing by separating the eyelids with fingers. Call a physician.

Handling and Storage

Storage
Keep tightly closed.

Hazards Identification

Inhalation
May be harmful if inhaled. Material may be irritating to mucous membranes and upper respiratory tract.
Skin
May cause skin irritation. May be harmful if absorbed through the skin.
Eyes
May cause eye irritation.
Ingestion
Harmful if swallowed.
Hazards
Emits toxic fumes under fire conditions.
EC Risk Phrase
22
EC Safety Phrase
36

Exposure Controls/Personal Protection

Personal Protection
Compatible chemical-resistant gloves. Chemical safety goggles.
Respirators
Government approved respirator.
Exposure Effects
Harmful. Harmful if swallowed. Target organ(s): Brain.

Fire Fighting Measures

Flash Point
244
Fire Fighting
Extinguish using Water spray. Carbon dioxide, dry chemical powder, or appropriate foam. Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.

Accidental Release Measures

Small spills/leaks
Sweep up, place in a bag and hold for waste disposal. Avoid raising dust. Ventilate area and wash spill site after material pickup is complete.

Stability and Reactivity

Stability
Stable at normal temperatures and pressures.
Incompatibilities
Strong oxidizing agents.
Decomposition
Carbon monoxide, Carbon dioxide, Nitrogen oxides.
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