Supplier Product Identification Physical and Chemical Properties First Aid Measures Handling and Storage Hazards Identification Exposure Controls/Personal Protection Fire Fighting Measures Accidental Release Measures Stability and Reactivity
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Niflumic acid(4394-00-7)

Supplier Product Identification Physical and Chemical Properties First Aid Measures Handling and Storage Hazards Identification Exposure Controls/Personal Protection Fire Fighting Measures Accidental Release Measures Stability and Reactivity

Product Identification

Product Name
Niflumic acid
Synonyms
2-(a,a,a-Trifluoro-m-toluidino)nicotinic acid
2-[[3-(Trifluoromethyl)phenyl]amino]-3-pyridinecarboxylic acid
2-[3-(Trifluoromethyl)anilino]nicotinic acid
2-[3-(Trifluoromethyl)phenylamino]nicotinic acid
Actol
CAS
4394-00-7
Formula
C13H9F3N2O2
Molecular Weight
282.22000000000003
EINECS
224-516-2
RTECS
QT2999100
RTECS Class
Drug; Reproductive Effector
Merck
12,6620
Beilstein/Gmelin
489360
Beilstein Reference
5-22-13-00598

Physical and Chemical Properties

Solubility in water
Slightly soluble
Melting Point
204
Boiling Point
378
Vapor Pressure
2E-6 (25 C)
pKa/pKb
1.68 (pKa)
Heat Of Vaporization
66.0 kJ/mol
Usage
Selective cyclooxygenase-2 (cox-2) inhibitor.

First Aid Measures

Ingestion
If swallowed, wash out mouth with water provided person is conscious. Call a physician.
Inhalation
If inhaled, remove to fresh air. If not breathing give artificial respiration. If breathing is difficult, give oxygen.
Skin
In case of contact, immediately wash skin with soap and copious amounts of water.
Eyes
In case of contact, immediately flush eyes with copious amounts of water for at least 15 minutes.

Handling and Storage

Storage
Keep tightly closed. Store in a cool dry place.

Hazards Identification

Inhalation
Material is irritating to mucous membranes and upper respiratory tract.
Hazards
Emits toxic fumes under fire conditions.
EC Risk Phrase
20/21/22 36/37/38
EC Safety Phrase
26 36

Exposure Controls/Personal Protection

Personal Protection
Rubber gloves. Chemical safety goggles.
Respirators
Government approved respirator.
Exposure Effects
Harmful by inhalation, in contact with skin and if swallowed. Irritating to eyes, respiratory system and skin.

Fire Fighting Measures

Flash Point
182
Fire Fighting
Extinguish using Water spray. Carbon dioxide, dry chemical powder, or appropriate foam. Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.

Accidental Release Measures

Small spills/leaks
Sweep up, place in a bag and hold for waste disposal. Avoid raising dust. Ventilate area and wash spill site after material pickup is complete.

Stability and Reactivity

Incompatibilities
Strong oxidizing agents.
Decomposition
Carbon monoxide, Carbon dioxide, Nitrogen oxides, Hydrogen fluoride.
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