Supplier Product Identification Physical and Chemical Properties First Aid Measures Handling and Storage Hazards Identification Exposure Controls/Personal Protection Fire Fighting Measures Accidental Release Measures Stability and Reactivity Transport Information
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4-Aminopyrazolo[3,4-d]pyrimidine(2380-63-4)

Supplier Product Identification Physical and Chemical Properties First Aid Measures Handling and Storage Hazards Identification Exposure Controls/Personal Protection Fire Fighting Measures Accidental Release Measures Stability and Reactivity Transport Information

Product Identification

Product Name
4-Aminopyrazolo[3,4-d]pyrimidine
Synonyms
1H-Pyrazolo[3,4-d]pyrimidin-4-amine
1H-Pyrazolo[3,4-d]pyrimidin-4-ylamine
4-Amino-1H-pyrazolo[3,4-d]pyrimidine
4-Aminopyrazolo[3,4-d]pyrimidine
Aminopurinol
Pyrazoloadenine
CAS
2380-63-4
Formula
C5H5N5
Molecular Weight
135.12
EINECS
219-174-6
RTECS
UR0717000
RTECS Class
Drug; Mutagen
Beilstein/Gmelin
5824
Beilstein Reference
4-26-00-03541

Physical and Chemical Properties

Appearance
Beige powder.
Solubility in water
Very soluble
Melting Point
325
pKa/pKb
8.96 (pKa)
Partition Coefficient
-.09
Vapor Density
4.7

First Aid Measures

Ingestion
If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.
Inhalation
Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Skin
Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
Eyes
Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.

Handling and Storage

Storage
Keep container closed when not in use. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.
Handling
Wash thoroughly after handling. Wash hands before eating. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Wash clothing before reuse.

Hazards Identification

Ingestion
Harmful if swallowed. May cause gastrointestinal irritation with nausea, vomiting and diarrhea.
Inhalation
May cause respiratory tract irritation. The toxicological properties of this substance have not been fully investigated.
Skin
May cause skin irritation. The toxicological properties of this material have not been fully investigated.
Eyes
May cause eye irritation. The toxicological properties of this material have not been fully investigated.
Hazards
Contact with metals may evolve flammable hydrogen gas.
EC Risk Phrase
R 25
EC Safety Phrase
S 22 36/37 45
UN (DOT)
1760

Exposure Controls/Personal Protection

Personal Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.

Fire Fighting Measures

Fire Fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Extinguishing media: Use agent most appropriate to extinguish fire. In case of fire use water spray, dry chemical, carbon dioxide, or appropriate foam.
Fire Potential
Non-combustible, substance itself does not burn but may decompose upon heating to produce corrosive and/or toxic fumes.

Accidental Release Measures

Small spills/leaks
Clean up spills immediately, using the appropriate protective equipment. Sweep up, then place into a suitable container for disposal. Avoid generating dusty conditions. Provide ventilation.

Stability and Reactivity

Incompatibilities
Oxidizing agents.
Stability
Stable under normal temperatures and pressures.
Decomposition
Irritating and toxic fumes and gases, nitrogen.
Combustion Products
Fire may produce irritating, corrosive and/or toxic gases.

Transport Information

UN Number
1760
Hazard Class
8
Packing Group
I; II; III
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