Terazosin(63590-64-7)
Supplier Product Identification
Physical and Chemical Properties
First Aid Measures
Handling and Storage
Hazards Identification
Exposure Controls/Personal Protection
Fire Fighting Measures
Accidental Release Measures
Stability and Reactivity
Product Identification
Product Name
Terazosin
Terazosin
Synonyms
1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-((tetrahydro-2-furanyl)carbonyl)piperazine
Methanone, [4-(4-amino-6,7-dimethoxy-2-quinazolinyl)-1-piperazinyl](tetrahydro-2-furanyl)-
Vasomet
1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-((tetrahydro-2-furanyl)carbonyl)piperazine
Methanone, [4-(4-amino-6,7-dimethoxy-2-quinazolinyl)-1-piperazinyl](tetrahydro-2-furanyl)-
Vasomet
CAS
63590-64-7
63590-64-7
Formula
C19H25N5O4
C19H25N5O4
Molecular Weight
387.44
387.44
RTECS
TK8044925
TK8044925
Merck
12,9297
12,9297
Physical and Chemical Properties
Appearance
White to off-white powder.
White to off-white powder.
Solubility in water
4 g/L (25 C)
4 g/L (25 C)
Melting Point
273
273
Boiling Point
665
665
Vapor Pressure
1.6E-17 (25 C)
1.6E-17 (25 C)
Density
1.33 g/cm3 (20 C)
1.33 g/cm3 (20 C)
pKa/pKb
7.55 (pKb)
7.55 (pKb)
Partition Coefficient
-.96
-.96
Heat Of Vaporization
97.72 kJ/mol
97.72 kJ/mol
Usage
1-Adrenoceptor antagonist.
1-Adrenoceptor antagonist.
First Aid Measures
Ingestion
If swallowed, wash out mouth with water provided person is conscious. Call a physician.
If swallowed, wash out mouth with water provided person is conscious. Call a physician.
Inhalation
If inhaled, remove to fresh air. If not breathing give artificial respiration. If breathing is difficult, give oxygen.
If inhaled, remove to fresh air. If not breathing give artificial respiration. If breathing is difficult, give oxygen.
Skin
In case of contact, immediately wash skin with soap and copious amounts of water. Remove contaminated clothing and shoes. Call a physician.
In case of contact, immediately wash skin with soap and copious amounts of water. Remove contaminated clothing and shoes. Call a physician.
Eyes
In case of contact with eyes, flush with copious amounts of water for at least 15 minutes. Assure adequate flushing by separating the eyelids with fingers. Call a physician.
In case of contact with eyes, flush with copious amounts of water for at least 15 minutes. Assure adequate flushing by separating the eyelids with fingers. Call a physician.
Handling and Storage
Storage
Keep tightly closed. Store in a cool dry place.
Keep tightly closed. Store in a cool dry place.
Hazards Identification
Inhalation
May be harmful if inhaled. Material may be irritating to mucous membranes and upper respiratory tract.
May be harmful if inhaled. Material may be irritating to mucous membranes and upper respiratory tract.
Skin
May cause skin irritation. May be harmful if absorbed through the skin.
May cause skin irritation. May be harmful if absorbed through the skin.
Eyes
May cause irritation.
May cause irritation.
Ingestion
Harmful if swallowed.
Harmful if swallowed.
Hazards
Emits toxic fumes under fire conditions.
Emits toxic fumes under fire conditions.
EC Risk Phrase
22
22
EC Safety Phrase
26
26
Exposure Controls/Personal Protection
Personal Protection
Compatible chemical-resistant gloves. Chemical safety goggles. Protective clothing.
Compatible chemical-resistant gloves. Chemical safety goggles. Protective clothing.
Exposure Effects
Target organs or systems: Cardiovascular system. Central nervous system. Dizziness and other signs of hypotension, facial flushing, and tachycardia. Exposure may cause nausea and vomiting.
Target organs or systems: Cardiovascular system. Central nervous system. Dizziness and other signs of hypotension, facial flushing, and tachycardia. Exposure may cause nausea and vomiting.
Fire Fighting Measures
Flash Point
355
355
Fire Fighting
Extinguish with water spray, carbon dioxide, dry chemical powder or appropriate foam. Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.
Extinguish with water spray, carbon dioxide, dry chemical powder or appropriate foam. Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.
Accidental Release Measures
Small spills/leaks
Sweep up, place in a bag and hold for waste disposal. Avoid raising dust. Ventilate area and wash spill site after material pickup is complete.
Sweep up, place in a bag and hold for waste disposal. Avoid raising dust. Ventilate area and wash spill site after material pickup is complete.
Stability and Reactivity
Stability
Stable at normal temperatures and pressures.
Stable at normal temperatures and pressures.
Incompatibilities
Strong oxidizing agents.
Strong oxidizing agents.
Decomposition
Carbon monoxide, Carbon dioxide, Nitrogen oxides.
Carbon monoxide, Carbon dioxide, Nitrogen oxides.
Contact
More
- Company Name:J & K SCIENTIFIC LTD.
- Tel:010-82848833 400-666-7788
- Fax:86-10-82849933
- WebSite:http://www.jkchemical.com
- Company Name:3B Pharmachem (Wuhan) International Co.,Ltd.
- Tel:821-50328103-801 18930552037
- Fax:86-21-50328109
- WebSite:https://www.chemicalbook.com/ShowSupplierProductsList13285/0.htm
- Company Name:LGM Pharma
- Tel:1-(800)-881-8210
- Fax:615-250-9817
- WebSite:http://www.lgmpharma.com
- Company Name:Shanghai Longsheng chemical Co.,Ltd.
- Tel:021-58099652-8005 13585536065
- Fax:021-58099609
- WebSite:http://www.shlschem.com
- Company Name:Chemsky(shanghai)International Co.,Ltd.
- Tel:021-50135380
- Fax:
- WebSite:http://www.shchemsky.com