Supplier Product Identification Physical and Chemical Properties First Aid Measures Handling and Storage Hazards Identification Exposure Controls/Personal Protection Fire Fighting Measures Accidental Release Measures Stability and Reactivity
Home > 5-Chloro-N-[2-[4-[[[(cyclohexylamino)carbonyl]-amino]sulfonyl]phenyl]-ethyl]-2-methoxybenzamide > 5-Chloro-N-[2-[4-[[[(cyclohexylamino)carbonyl]-amino]sulfonyl]phenyl]-ethyl]-2-methoxybenzamide(10238-21-8)

5-Chloro-N-[2-[4-[[[(cyclohexylamino)carbonyl]-amino]sulfonyl]phenyl]-ethyl]-2-methoxybenzamide(10238-21-8)

Supplier Product Identification Physical and Chemical Properties First Aid Measures Handling and Storage Hazards Identification Exposure Controls/Personal Protection Fire Fighting Measures Accidental Release Measures Stability and Reactivity

Product Identification

Product Name
5-Chloro-N-[2-[4-[[[(cyclohexylamino)carbonyl]-amino]sulfonyl]phenyl]-ethyl]-2-methoxybenzamide
Synonyms
5-Chloro-N-[4-(cyclohexylureidosulfonyl)phenethyl]-2-methoxybenzamide
Glyburide
N-p-[2-(5-Chloro-2-methoxybenzamido)ethyl]benzenesulfonyl-N'-cyclohexylurea
CAS
10238-21-8
Formula
C23H28ClN3O5S
Molecular Weight
494.01
EINECS
233-570-6
RTECS
YS4725200
RTECS Class
Drug; Reproductive Effector; Human Data
Merck
13,4491
Beilstein/Gmelin
2230085
Beilstein Reference
6-14

Physical and Chemical Properties

Appearance
White solid
Solubility in water
1.1 mg/L (37 C)
Melting Point
168 - 172
Density
1.38 g/cm3
pKa/pKb
5.3(at 25℃) (pKa)
Usage
Hypoglycemic drug.

First Aid Measures

Ingestion
If swallowed, wash out mouth with water provided person is conscious. Call a physician.
Inhalation
If inhaled, remove to fresh air. If breathing becomes difficult, call a physician.
Skin
In case of contact, immediately wash skin with soap and copious amounts of water.
Eyes
In case of contact with eyes, flush with copious amounts of water for at least 15 minutes. Assure adequate flushing by separating the eyelids with fingers. Call a physician.

Handling and Storage

Storage
Keep tightly closed. Store at 2-8 C

Hazards Identification

Inhalation
May be harmful if inhaled. Material may be irritating to mucous membranes and upper respiratory tract.
Skin
May cause skin irritation. May be harmful if absorbed through the skin.
Eyes
May cause eye irritation.
Ingestion
May be harmful if swallowed.
Hazards
Emits toxic fumes under fire conditions.

Exposure Controls/Personal Protection

Personal Protection
Protective gloves. Chemical safety goggles.
Respirators
Wear dust mask.
Exposure Effects
Avoid contact and inhalation. Target organ(s): Pancreas. G.I. System.

Fire Fighting Measures

Fire Fighting
Extinguish using Water spray. Carbon dioxide, dry chemical powder, or appropriate foam. Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.

Accidental Release Measures

Small spills/leaks
Sweep up, place in a bag and hold for waste disposal. Avoid raising dust. Ventilate area and wash spill site after material pickup is complete.

Stability and Reactivity

Stability
Stable at normal temperatures and pressures.
Incompatibilities
Strong oxidizing agents.
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