PNCB(100-00-5)
Product Identification
Physical and Chemical Properties
First Aid Measures
Handling and Storage
Hazards Identification
Exposure Controls/Personal Protection
Fire Fighting Measures
Accidental Release Measures
Stability and Reactivity
Transport Information
Product Identification
Product Name
PNCB
PNCB
Synonyms
1-Chloro-4-nitrobenzene
4-Chloronitrobenzene
p-Chloronitrobenzene
1-Chloro-4-nitrobenzene
4-Chloronitrobenzene
p-Chloronitrobenzene
CAS
100-00-5
100-00-5
Formula
C6H4ClNO2
C6H4ClNO2
Molecular Weight
157.56
157.56
EINECS
202-809-6
202-809-6
RTECS
CZ1050000
CZ1050000
RTECS Class
Tumorigen; Mutagen; Reproductive Effector
Tumorigen; Mutagen; Reproductive Effector
Merck
13,2170
13,2170
Beilstein/Gmelin
508691
508691
Beilstein Reference
4-05-00-00723
4-05-00-00723
EC Index Number
610-005-00-5
610-005-00-5
EC Class
Toxic; Danger of cumulative effects; Dangerous for the Environment
Toxic; Danger of cumulative effects; Dangerous for the Environment
Physical and Chemical Properties
Appearance
Light yellow crystalline solid. Sweet odor.
Light yellow crystalline solid. Sweet odor.
Solubility in water
0.21 g/L (20 C)
0.21 g/L (20 C)
Melting Point
83
83
Boiling Point
239
239
Vapor Pressure
0.09 (25 C)
0.09 (25 C)
Density
1.52 g/cm3 (20 C)
1.52 g/cm3 (20 C)
Partition Coefficient
2.39
2.39
Heat Of Vaporization
62.1 kJ/mol
62.1 kJ/mol
Heat Of Combustion
-2909 kJ/mol
-2909 kJ/mol
Usage
P-chloronitrobenzene is used to manufacture p-nitrophenol, p-nitroaniline, p-aminophenol, phenacetin, acetominophen, parathion and other agricultural chemicals, rubber chemicals, antioxidants, oil additives and dapsone (an antimalarial drug).
P-chloronitrobenzene is used to manufacture p-nitrophenol, p-nitroaniline, p-aminophenol, phenacetin, acetominophen, parathion and other agricultural chemicals, rubber chemicals, antioxidants, oil additives and dapsone (an antimalarial drug).
Vapor Density
5.44
5.44
Refractive Index
1.5376 (100 C)
1.5376 (100 C)
First Aid Measures
Ingestion
Never give anything by mouth to an unconscious person. Get medical aid immediately. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
Never give anything by mouth to an unconscious person. Get medical aid immediately. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
Inhalation
Get medical aid immediately. Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. DO NOT use mouth-to-mouth respiration.
Get medical aid immediately. Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. DO NOT use mouth-to-mouth respiration.
Skin
Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
Eyes
Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.
Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.
Handling and Storage
Storage
Store in a cool, dry place. Store in a cool, dry, well-ventilated area away from incompatible substances. Keep containers tightly closed.
Store in a cool, dry place. Store in a cool, dry, well-ventilated area away from incompatible substances. Keep containers tightly closed.
Handling
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use only in a well ventilated area. Avoid contact with skin and eyes. Do not ingest or inhale.
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use only in a well ventilated area. Avoid contact with skin and eyes. Do not ingest or inhale.
Hazards Identification
Inhalation
May cause effects similar to those described for ingestion. Methemoglobinemia is characterized by dizziness, drowsiness, headache, breath shortness, cyanosis with bluish skin, rapid heart rate and chocolate-brown blood.
May cause effects similar to those described for ingestion. Methemoglobinemia is characterized by dizziness, drowsiness, headache, breath shortness, cyanosis with bluish skin, rapid heart rate and chocolate-brown blood.
Skin
Causes skin irritation. May cause skin sensitization, an allergic reaction, which becomes evident upon re-exposure to this material.
Causes skin irritation. May cause skin sensitization, an allergic reaction, which becomes evident upon re-exposure to this material.
Eyes
Causes eye irritation.
Causes eye irritation.
Ingestion
Harmful if swallowed. Aspiration of material into the lungs may cause chemical pneumonitis, which may be fatal. Methemoglobinemia is characterized by dizziness, drowsiness, headache, breath shortness, cyanosis with bluish skin, rapid heart rate and chocolate-brown colored blood. May cause central nervous system depression.
Harmful if swallowed. Aspiration of material into the lungs may cause chemical pneumonitis, which may be fatal. Methemoglobinemia is characterized by dizziness, drowsiness, headache, breath shortness, cyanosis with bluish skin, rapid heart rate and chocolate-brown colored blood. May cause central nervous system depression.
Hazards
Containers may explode when heated.
Containers may explode when heated.
EC Risk Phrase
R 23/24/25 33 51/53
R 23/24/25 33 51/53
EC Safety Phrase
S 28 36/37 45 61
S 28 36/37 45 61
UN (DOT)
1578
1578
Exposure Controls/Personal Protection
Personal Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves and clothing to prevent skin exposure. Clothing: Wear appropriate protective clothing to minimize contact with skin.
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves and clothing to prevent skin exposure. Clothing: Wear appropriate protective clothing to minimize contact with skin.
Respirators
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Exposure Effects
May cause liver and kidney damage. Absorption into the body leads to the formation of methemoglobin which in sufficient concentrations causes cyanosis. May cause anemia and other blood cell abnormalities. May cause fatigue, dizziness, headache, insomnia and weight loss.
May cause liver and kidney damage. Absorption into the body leads to the formation of methemoglobin which in sufficient concentrations causes cyanosis. May cause anemia and other blood cell abnormalities. May cause fatigue, dizziness, headache, insomnia and weight loss.
Exposure limit(s)
TLV: 0.1 ppm; 0.64 mg/m3 (as TWA) A3 (skin) (ACGIH 1997). OSHA PEL: TWA 1 mg/m3 skin NIOSH REL: Ca See Appendix A skin NIOSH IDLH: Potential occupational carcinogen 100 mg/m3
TLV: 0.1 ppm; 0.64 mg/m3 (as TWA) A3 (skin) (ACGIH 1997). OSHA PEL: TWA 1 mg/m3 skin NIOSH REL: Ca See Appendix A skin NIOSH IDLH: Potential occupational carcinogen 100 mg/m3
Poison Class
4
4
Fire Fighting Measures
Flash Point
95
95
Autoignition
515
515
Fire Fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Containers may explode when heated. To extinguish fire, use water, dry chemical, chemical foam, or alcohol-resistant foam. Cool containers with flooding quantities of water until well after fire is out.
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Containers may explode when heated. To extinguish fire, use water, dry chemical, chemical foam, or alcohol-resistant foam. Cool containers with flooding quantities of water until well after fire is out.
Upper exp. limit
8.8
8.8
Fire Potential
This compound is combustible.
This compound is combustible.
Accidental Release Measures
Small spills/leaks
Clean up spills immediately, using the appropriate protective equipment. Sweep up, then place into a suitable container for disposal. Avoid generating dusty conditions. Remove all sources of ignition. Provide ventilation.
Clean up spills immediately, using the appropriate protective equipment. Sweep up, then place into a suitable container for disposal. Avoid generating dusty conditions. Remove all sources of ignition. Provide ventilation.
Stability and Reactivity
Disposal Code
9
9
Incompatibilities
Oxidizing agents.
Oxidizing agents.
Stability
Stable under normal temperatures and pressures.
Stable under normal temperatures and pressures.
Decomposition
Hydrogen chloride, nitrogen oxides, carbon monoxide, irritating and toxic fumes and gases, carbon dioxide, nitrogen.
Hydrogen chloride, nitrogen oxides, carbon monoxide, irritating and toxic fumes and gases, carbon dioxide, nitrogen.
Combustion Products
Fire may produce irritating, corrosive and/or toxic gases.
Fire may produce irritating, corrosive and/or toxic gases.
Transport Information
UN Number
1578
1578
Hazard Class
6.1
6.1
Packing Group
II
II
HS Code
2904 90 85
2904 90 85