Supplier Product Identification Physical and Chemical Properties First Aid Measures Handling and Storage Exposure Controls/Personal Protection Fire Fighting Measures Accidental Release Measures Stability and Reactivity
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Erythromycin ethylsuccinate (1264-62-6)

Supplier Product Identification Physical and Chemical Properties First Aid Measures Handling and Storage Exposure Controls/Personal Protection Fire Fighting Measures Accidental Release Measures Stability and Reactivity

Product Identification

Product Name
Erythromycin ethylsuccinate
Synonyms
Eritrocina
Erythromycin, 2'-(ethyl butanedioate)
Ethyl [(2R,3S,4R,6S)-4-dimethylamino-2-[[(3R,4S,5S,6R,7R,9R,11R,12R,13R,14R)-14-ethyl-7,12,13-trihydroxy-4-[(2S,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyl-oxan-2-yl]oxy-3,5,7,9,11,13-hexamethyl-2,10-dioxo-1-oxacyclotetradec-6-yl]oxy]-6-methyl-oxan-3-yl] butanedioate
Monomycin
Paediathrocin
Succinic acid, monoester with erythromycin
CAS
1264-62-6
Formula
C43H75NO16
Molecular Weight
862.06
EINECS
215-033-8
RTECS
WM9800000
RTECS Class
Drug; Human Data
Beilstein/Gmelin
77638
Beilstein Reference
4-18-00-07416

Physical and Chemical Properties

Appearance
Crystals.
Solubility in water
Insoluble
Melting Point
109 - 110
pKa/pKb
6.42 (pKb)
Usage
Medication.

First Aid Measures

Ingestion
Seek medical attention. If individual is drowsy or unconscious, do not give anything by mouth; place individual on the left side with the head down. Contact a physician, medical facility, or poison control center for advice about whether to induce vomiting. If possible, do not leave individual unattended.
Inhalation
If symptoms develop, move individual away from exposure and into fresh air. If symptoms persist, seek medical attention. If breathing is difficult, administer oxygen. Keep person warm and quiet; seek immediate medical attention.
Skin
Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes.
Eyes
If symptoms develop, immediately move individual away from exposure and into fresh air. Flush eyes gently with water for at least 15 minutes while holding eyelids apart; seek immediate medical attention.

Handling and Storage

Storage
Keep in a cool, dry, well-ventilated area in a sealed container.
Handling
Keep container closed when not in use. Avoid contact. Follow label directions.

Exposure Controls/Personal Protection

Personal Protection
Chemical splash goggles in compliance with OSHA regulations are advised; however, OSHA regulations also permit other type safety glasses. Whre chemical resistant gloves. To prevent repeated or prolonged skin contact, wear impervious clothing and boots.
Respirators
Where environmental controls are lacking or in an enclosed space, use a NIOSH/MSHA approved respirator for dust.
Exposure Effects
Allergic skin and respiratory reactions have been reported.

Fire Fighting Measures

Fire Fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Use agent most appropriate to extinguish fire.

Accidental Release Measures

Small spills/leaks
Ventilate area. Use protective eqiupment. Sweep or vacuum up. Do not creat dust. Place in a dry container for disposal. Clean spill area with water.

Stability and Reactivity

Stability
Stable.
Incompatibilities
Strong oxidizing agents.
Decomposition
None reported.
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