Supplier Product Identification Physical and Chemical Properties First Aid Measures Handling and Storage Hazards Identification Exposure Controls/Personal Protection Fire Fighting Measures Accidental Release Measures Stability and Reactivity Transport Information
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2-(1-Naphthylmethyl)imidazoline hydrochloride(550-99-2)

Supplier Product Identification Physical and Chemical Properties First Aid Measures Handling and Storage Hazards Identification Exposure Controls/Personal Protection Fire Fighting Measures Accidental Release Measures Stability and Reactivity Transport Information

Product Identification

Product Name
2-(1-Naphthylmethyl)imidazoline hydrochloride
Synonyms
2-(1-Naphthylmethyl)-2-imidazoline hydrochloride
2-Imidazoline, 2-(1-naphthylmethyl)-, monohydrochloride
CAS
550-99-2
Formula
C14H15ClN2
Molecular Weight
246.76
EINECS
208-989-2
RTECS
NJ4375000
RTECS Class
Drug; Human Data
Merck
12,6455
Beilstein/Gmelin
3716843
Beilstein Reference
5-23-08-00293

Physical and Chemical Properties

Appearance
White powder.
Solubility in water
170 g/L
Melting Point
258 - 259
pKa/pKb
pKa (25°C) 10.35 ±0.02, (35°C) 10.13 ±0.02, (45°C) 9.92 ±0.03; pKa (25°C) 10.35 ±0.02, (35°C) 10.13 ±0.02, (45°C) 9.92 ±0.03 (pKa)
Usage
Nasal decongestant.

First Aid Measures

Ingestion
Never give anything by mouth to an unconscious person. Get medical aid immediately. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
Inhalation
Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid. DO NOT use mouth-to-mouth respiration.
Skin
Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
Eyes
Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.

Handling and Storage

Storage
Keep containers tightly closed. Store in a cool, dry area away from incompatible substances.
Handling
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use only in a well ventilated area. Use with adequate ventilation. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Avoid ingestion and inhalation.

Hazards Identification

Inhalation
Inhalation of high concentrations may cause central nervous system effects characterized by headache, dizziness, unconsciousness and coma. Inhalation may produce headache, dizziness, blurred vision, lowered blood pressure, slow pulse and respiratory tract irritation.
Skin
May cause skin irritation.
Eyes
May cause eye irritation.
Ingestion
May cause central nervous system depression, characterized by excitement, followed by headache, dizziness, drowsiness, and nausea. Advanced stages may cause collapse, unconsciousness, coma and possible death due to respiratory failure.
EC Risk Phrase
R 25
EC Safety Phrase
S 22 36/37 45
UN (DOT)
2811

Exposure Controls/Personal Protection

Personal Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators
A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use.
Exposure Effects
Repeated exposure may cause loss or impairment of smell.

Fire Fighting Measures

Fire Fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. To extinguish fire, use water, dry chemical, chemical foam, or alcohol-resistant foam.

Accidental Release Measures

Small spills/leaks
Sweep up, then place into a suitable container for disposal. Avoid generating dusty conditions. Provide ventilation.

Stability and Reactivity

Incompatibilities
Direct light, aluminum, strong oxidizing agents.
Stability
Stable under normal temperatures and pressures.
Decomposition
Hydrogen chloride, nitrogen oxides, carbon monoxide, irritating and toxic fumes and gases, carbon dioxide, nitrogen.

Transport Information

UN Number
2811
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