Supplier Product Identification Physical and Chemical Properties First Aid Measures Handling and Storage Exposure Controls/Personal Protection Fire Fighting Measures Accidental Release Measures Stability and Reactivity Transport Information Hazards Identification
Home > 14,15b-Epoxy-3b,5a,16b-trihydroxy-5b,20(22)-bufadienolide 16-acetate > 14,15b-Epoxy-3b,5a,16b-trihydroxy-5b,20(22)-bufadienolide 16-acetate(1108-68-5)

14,15b-Epoxy-3b,5a,16b-trihydroxy-5b,20(22)-bufadienolide 16-acetate(1108-68-5)

Supplier Product Identification Physical and Chemical Properties First Aid Measures Handling and Storage Exposure Controls/Personal Protection Fire Fighting Measures Accidental Release Measures Stability and Reactivity Transport Information Hazards Identification

Product Identification

Product Name
14,15b-Epoxy-3b,5a,16b-trihydroxy-5b,20(22)-bufadienolide 16-acetate
Synonyms
14,15-Epoxy-14H-cyclopenta[a]phenanthrene, bufa-20,22-dienolide deriv.
5-b-Bufa-20,22-dienolide, 14,15-b-epoxy-3-b,5,16-b-trihydroxy, 16-acetate
Bufa-20,22-dienolide, 16- (acetyloxy)-14,15-epoxy-3,5-dihydroxy-, (3.beta.,5.beta.,15.beta.,16.beta.)-
CAS
1108-68-5
Formula
C26H34O7
Molecular Weight
458.55
RTECS
EI2991000
Merck
12,2367

Physical and Chemical Properties

Solubility in water
.73
Melting Point
259 - 262
Boiling Point
627
Vapor Pressure
2.3E-18 (25 C)
Density
1.34 kJ/mol
pKa/pKb
14.67 (pKa)
Partition Coefficient
.87
Heat Of Vaporization
106/4 kJ/mol

First Aid Measures

Ingestion
If swallowed, wash out mouth with water provided person is conscious. Call a physician.
Inhalation
If inhaled, remove to fresh air. If not breathing give artificial respiration. If breathing is difficult, give oxygen.
Skin
In case of contact, immediately wash skin with soap and copious amounts of water. Remove contaminated clothing and shoes. Call a physician.
Eyes
In case of contact with eyes, flush with copious amounts of water for at least 15 minutes. Assure adequate flushing by separating the eyelids with fingers. Call a physician.

Handling and Storage

Storage
Store at 2 - 8 C.

Exposure Controls/Personal Protection

Personal Protection
Compatible chemical-resistant gloves. Chemical safety goggles. Protective clothing.
Respirators
Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU). Where risk assessment shows air-purifying respirators are appropriate use a full-face particle respirator type N100 (US) or type P3 (EN 143) respirator cartridges as a backup to engineering controls. If the respirator is the sole means of protection, use a full-face supplied air respirator.
Exposure Effects
May be fatal if inhaled, swallowed, or absorbed through skin. Toad venoms are cardioactive and can cause death by disturbing the normal heart rhythm. The mucous membrane that lines the mouth is a means of introducing the venom into the bloodstream. (Venomous Animals and Their Venoms, vol. II: Bucherl, W. Editor).

Fire Fighting Measures

Flash Point
210
Fire Fighting
Extinguish with water spray, carbon dioxide, dry chemical powder or appropriate foam. Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.

Accidental Release Measures

Small spills/leaks
Carefully sweep up and remove. Place in appropriate container. Avoid raising dust. Ventilate area and wash spill site after material pickup is complete.

Stability and Reactivity

Incompatibilities
Moisture.
Stability
Stable at normal temperatures and pressures.
Decomposition
Oxides of carbon.

Transport Information

UN Number
2811
Hazard Class
6.1
Packing Group
I

Hazards Identification

Hazards
Emits toxic fumes under fire conditions.
EC Risk Phrase
26/27/28
EC Safety Phrase
22 36/37/39 45
UN (DOT)
2811
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