Home > (1S,2S)-(+)-Pseudoephedrine hydrochloride > (1S,2S)-(+)-Pseudoephedrine hydrochloride(345-78-8)
(1S,2S)-(+)-Pseudoephedrine hydrochloride(345-78-8)
Product Identification
Physical and Chemical Properties
First Aid Measures
Handling and Storage
Hazards Identification
Exposure Controls/Personal Protection
Fire Fighting Measures
Accidental Release Measures
Stability and Reactivity
Product Identification
Product Name
(1S,2S)-(+)-Pseudoephedrine hydrochloride
(1S,2S)-(+)-Pseudoephedrine hydrochloride
Synonyms
(1S,2S)-2-Methylamino-1-phenyl-propan-1-ol hydrochloride
Benzenemethanol, a-[(1S)-1-(methylamino)ethyl]-, hydrochloride, (aS)-
d-(1S,2S)-Pseudoephedrine hydrochloride
d-[a-(1-Methylamino)ethyl]benzyl alcohol hydrochloride
Novafed
Sudafed
(1S,2S)-2-Methylamino-1-phenyl-propan-1-ol hydrochloride
Benzenemethanol, a-[(1S)-1-(methylamino)ethyl]-, hydrochloride, (aS)-
d-(1S,2S)-Pseudoephedrine hydrochloride
d-[a-(1-Methylamino)ethyl]benzyl alcohol hydrochloride
Novafed
Sudafed
CAS
345-78-8
345-78-8
Formula
C10H16ClNO
C10H16ClNO
Molecular Weight
201.69
201.69
EINECS
206-462-1
206-462-1
RTECS
UL5950000
UL5950000
RTECS Class
Drug; Human Data
Drug; Human Data
Beilstein/Gmelin
3915112
3915112
Beilstein Reference
4-13-00-01878
4-13-00-01878
Physical and Chemical Properties
Appearance
White crystalline powder.
White crystalline powder.
Melting Point
183 - 186
183 - 186
Density
1.198 g/cm3
1.198 g/cm3
pKa/pKb
9.22(at 25℃) (pKa)
9.22(at 25℃) (pKa)
Heat Of Vaporization
Usage
Medication.
Medication.
First Aid Measures
Ingestion
If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.
If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.
Inhalation
Get medical aid immediately. Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.
Get medical aid immediately. Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.
Skin
Get medical aid immediately. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes.
Get medical aid immediately. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes.
Eyes
Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.
Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.
Handling and Storage
Storage
Store in a cool, dry place.
Store in a cool, dry place.
Handling
Wash thoroughly after handling. Use only in a well ventilated area. Avoid contact with eyes, skin, and clothing. Avoid ingestion and inhalation.
Wash thoroughly after handling. Use only in a well ventilated area. Avoid contact with eyes, skin, and clothing. Avoid ingestion and inhalation.
Hazards Identification
Inhalation
The toxicological properties of this substance have not been fully investigated.
The toxicological properties of this substance have not been fully investigated.
Skin
May cause skin irritation.
May cause skin irritation.
Eyes
May cause eye irritation.
May cause eye irritation.
Ingestion
May cause irritation of the digestive tract. May be harmful if swallowed. May cause central nervous system effects and/or neurological effects.
May cause irritation of the digestive tract. May be harmful if swallowed. May cause central nervous system effects and/or neurological effects.
Exposure Controls/Personal Protection
Personal Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Exposure Effects
Prolonged or repeated exposure can cause psychic abnormalities such as anxiety, depression and excitability. Prolonged exposure may cause mental changes such as hallucinations, depression, psychosis, and possibly coma. Repeated or prolonged exposure may cause CNS stimulation.
Prolonged or repeated exposure can cause psychic abnormalities such as anxiety, depression and excitability. Prolonged exposure may cause mental changes such as hallucinations, depression, psychosis, and possibly coma. Repeated or prolonged exposure may cause CNS stimulation.
Fire Fighting Measures
Fire Fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Extinguishing media: Use extinguishing media most appropriate for the surrounding fire.
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Extinguishing media: Use extinguishing media most appropriate for the surrounding fire.
Accidental Release Measures
Small spills/leaks
Sweep up or absorb material, then place into a suitable clean, dry, closed container for disposal.
Sweep up or absorb material, then place into a suitable clean, dry, closed container for disposal.
Stability and Reactivity
Incompatibilities
Light, strong oxidizing agents.
Light, strong oxidizing agents.
Stability
Stable under normal temperatures and pressures.
Stable under normal temperatures and pressures.
Decomposition
Carbon dioxide and carbon monoxide, hydrogen chloride gas, nitrogen oxides, various hydrocarbons.
Carbon dioxide and carbon monoxide, hydrogen chloride gas, nitrogen oxides, various hydrocarbons.