Supplier Product Identification Physical and Chemical Properties First Aid Measures Handling and Storage Hazards Identification Exposure Controls/Personal Protection Fire Fighting Measures Accidental Release Measures Stability and Reactivity Transport Information
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L-Histidine hydrochloride monohydrate(5934-29-2)

Supplier Product Identification Physical and Chemical Properties First Aid Measures Handling and Storage Hazards Identification Exposure Controls/Personal Protection Fire Fighting Measures Accidental Release Measures Stability and Reactivity Transport Information

Product Identification

Product Name
L-Histidine hydrochloride monohydrate
Synonyms
(2S)-2-Amino-3-(3H-imidazol-4-yl)propanoic acid hydrate hydrochloride
L-Histidine hydrochloride hydrate
CAS
5934-29-2
Formula
C6H12ClN3O3
Molecular Weight
209.63
EINECS
211-438-9
RTECS
MS3119000
RTECS Class
Other
Merck
13,4741
Beilstein/Gmelin
4168261
Beilstein Reference
4-25-00-04343

Physical and Chemical Properties

Appearance
White crystals.
Solubility in water
169.9 g/L (20 C)
Melting Point
259
Density
1.485 g/cm3
Usage
Histamine is involved in local immune responses, regulating physiological function in the gut and as a neurotransmitter.

First Aid Measures

Ingestion
If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.
Inhalation
Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Skin
Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes.
Eyes
Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.

Handling and Storage

Storage
Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.
Handling
Wash thoroughly after handling. Use with adequate ventilation. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation.

Hazards Identification

Ingestion
The toxicological properties of this substance have not been fully investigated.
Inhalation
The toxicological properties of this substance have not been fully investigated.
Skin
No information regarding skin irritation and other potential effects was found.
Eyes
No information regarding eye irritation and other potential effects was found.
EC Risk Phrase
R 36/37/38
EC Safety Phrase
S 26 36

Exposure Controls/Personal Protection

Personal Protection
Eyes: Wear chemical goggles. Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.

Fire Fighting Measures

Fire Fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Extinguishing media: Use agent most appropriate to extinguish fire.

Accidental Release Measures

Small spills/leaks
Sweep up or absorb material, then place into a suitable clean, dry, closed container for disposal. Avoid generating dusty conditions.

Stability and Reactivity

Incompatibilities
Oxidizing agents.
Stability
Stable under normal temperatures and pressures.
Decomposition
Nitrogen oxides, carbon monoxide, carbon dioxide.

Transport Information

HS Code
29332990
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