Supplier Product Identification Physical and Chemical Properties First Aid Measures Handling and Storage Hazards Identification Exposure Controls/Personal Protection Fire Fighting Measures Accidental Release Measures Stability and Reactivity
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Betulin(473-98-3)

Supplier Product Identification Physical and Chemical Properties First Aid Measures Handling and Storage Hazards Identification Exposure Controls/Personal Protection Fire Fighting Measures Accidental Release Measures Stability and Reactivity

Product Identification

Product Name
Betulin
Synonyms
3b,28-Dihydroxylup-20(29)-ene
Betulinic alcohol
Betulinol
Lup-20(29)-ene-3,28-diol, (3b)-
Lup-20(30)-ene-3b,28-diol
CAS
473-98-3
Formula
C30H50O2
Molecular Weight
442.73
EINECS
207-475-5
Merck
12,1237

Physical and Chemical Properties

Solubility in water
Insoluble
Melting Point
256 - 257
Vapor Pressure
4.3E-13 (25 C)
Density
1.156 g/cm3 (20 C)
pKa/pKb
14.83 (pKa)
Partition Coefficient
9.01
Usage
Exhibits anti-malarial, anti-inflamatory and anti-hiv activity as well as showing cytotoxicity towards a number of tumour cell lines.
Refractive Index
1.5186

First Aid Measures

Ingestion
Do not induce vomiting without medical advice.
Inhalation
Move to fresh air. Call a physician immediately.
Skin
Rinse immediately with plenty of water and seek medical advice.
Eyes
In the case of contact with eyes, rinse immediately with plenty of water and seek medical advice.

Handling and Storage

Storage
Store at 4 C. Store under nitrogen.

Hazards Identification

Inhalation
May cause irritation of respiratory tract.
Skin
May cause allergic skin reaction.
Eyes
Causes irritation.
Ingestion
May be harmful if swallowed.

Exposure Controls/Personal Protection

Personal Protection
PVC or plastic material gloves. Safety glasses with side shields.
Exposure Effects
Chronic exposure may cause nausea and vomiting, higher exposure causes unconsciousness. Symptoms of overexposure may be headache, dizziness, tiredness, nausea and vomiting.

Fire Fighting Measures

Fire Fighting
Use dry chemical, CO2, water spray or alcohol foam. wear self-contained breathing apparatus pressure-demand, MSHA/NIOSH (approved or equivalent) and full protective gear

Accidental Release Measures

Small spills/leaks
Eliminate all ignition sources. Absorb and/or contain spill with inert material(s e.g., sand, vermiculite). Then place in appropriate container.

Stability and Reactivity

Stability
Stable under recommended storage conditions. Material is air and moisture sensitive.
Incompatibilities
Strong oxidizing agents.
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