Supplier Product Identification Physical and Chemical Properties First Aid Measures Handling and Storage Hazards Identification Exposure Controls/Personal Protection Fire Fighting Measures Accidental Release Measures Stability and Reactivity
Home > Carbamazepine > Carbamazepine(298-46-4)

Carbamazepine(298-46-4)

Supplier Product Identification Physical and Chemical Properties First Aid Measures Handling and Storage Hazards Identification Exposure Controls/Personal Protection Fire Fighting Measures Accidental Release Measures Stability and Reactivity

Product Identification

Product Name
Carbamazepine
Synonyms
5-Carbamoyl-5H-dibenz(b,f)azepine
5-Carbamoyldibenzo(b,f)azepine
5H-Dibenz(b,f)azepine-5-carboxamide
Carbazepine
Dibenz(b,f)azepine-5-carboxamide
Telesmin
CAS
298-46-4
Formula
C15H12N2O
Molecular Weight
236.27
EINECS
206-062-7
RTECS
HN8225000
RTECS Class
Drug; Mutagen; Reproductive Effector; Human Data
Merck
12,1826
Beilstein/Gmelin
1246090
Beilstein Reference
5-20-08-00247

Physical and Chemical Properties

Appearance
Crystals from absorption in ethanol + benzene.
Solubility in water
Insoluble
Melting Point
190 - 192
Boiling Point
411
Vapor Pressure
6E-7 (25 C)
Density
1.296 g/cm3 (-115 C)
pKa/pKb
13.94 (pKa)
Partition Coefficient
2.67
Heat Of Vaporization
66.3 kJ/mol
Usage
Medication.

First Aid Measures

Ingestion
Get medical aid. Wash mouth out with water.
Inhalation
Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Skin
Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes.
Eyes
Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.

Handling and Storage

Storage
Store in a cool, dry place. Store in a tightly closed container.
Handling
Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes.

Hazards Identification

Inhalation
May cause respiratory tract irritation.
Skin
May cause skin sensitization, an allergic reaction, which becomes evident upon re-exposure to this material.
Eyes
May cause eye irritation.
Ingestion
Harmful if swallowed. May cause irritation of the digestive tract.

Exposure Controls/Personal Protection

Personal Protection
Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Exposure Effects
Ataxia, slurred speech, nystagmus, dystonias, and varying degrees of CNS depression are common. Myoclonic activity, seizures and abnormal tendon reflexes have been reported. Cyclic coma, possibly due to delayed absorption, has been reported.

Fire Fighting Measures

Flash Point
202
Fire Fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. To extinguish fire use water spray, dry chemical, carbon dioxide, or chemical foam.

Accidental Release Measures

Small spills/leaks
Vacuum or sweep up material and place into a suitable disposal container.

Stability and Reactivity

Stability
Stable under normal temperatures and pressures.
Incompatibilities
Strong oxidizing agents.
Decomposition
Nitrogen oxides, carbon monoxide, carbon dioxide.
Contact More