Supplier Product Identification Physical and Chemical Properties First Aid Measures Handling and Storage Hazards Identification Exposure Controls/Personal Protection Fire Fighting Measures Accidental Release Measures Stability and Reactivity
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D-Serine(312-84-5)

Supplier Product Identification Physical and Chemical Properties First Aid Measures Handling and Storage Hazards Identification Exposure Controls/Personal Protection Fire Fighting Measures Accidental Release Measures Stability and Reactivity

Product Identification

Product Name
D-Serine
Synonyms
(2R)-2-Amino-3-hydroxypropanoic acid
(R)-Serine
CAS
312-84-5
Formula
C3H7NO3
Molecular Weight
105.09
EINECS
206-229-4
Merck
12,8604
Beilstein/Gmelin
1721403
Beilstein Reference
4-04-00-03118

Physical and Chemical Properties

Appearance
White solid.
Solubility in water
Very soluble
Melting Point
235
pKa/pKb
2.16 (pKa)
Partition Coefficient
-1.75
Usage
The l-form is one of the 20 naturally occurring proteinogenic amino acids. The d form serves as a neuronal signal by activating nmda receptors in the brain.

First Aid Measures

Ingestion
If victim is conscious and alert, give 2-4 cupfuls of milk or water. Get medical aid.
Inhalation
Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid if cough or other symptoms appear.
Skin
Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Get medical aid if irritation develops or persists.
Eyes
Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.

Handling and Storage

Storage
Store in a cool, dry place. Store in a tightly closed container.
Handling
Wash thoroughly after handling. Avoid contact with skin and eyes. Avoid ingestion and inhalation.

Hazards Identification

Ingestion
The toxicological properties of this substance have not been fully investigated.
Inhalation
May cause respiratory tract irritation.
Skin
May cause skin irritation.
Eyes
May cause eye irritation.

Exposure Controls/Personal Protection

Personal Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to minimize contact with skin.
Respirators
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.

Fire Fighting Measures

Fire Fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. To extinguish fire use water spray, dry chemical, carbon dioxide, or chemical foam.

Accidental Release Measures

Small spills/leaks
Vacuum or sweep up material and place into a suitable disposal container.

Stability and Reactivity

Stability
Stable under normal temperatures and pressures.
Incompatibilities
Strong oxidizing agents.
Decomposition
Nitrogen oxides, carbon monoxide, carbon dioxide.
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