Supplier Product Identification Physical and Chemical Properties First Aid Measures Handling and Storage Exposure Controls/Personal Protection Fire Fighting Measures Accidental Release Measures Stability and Reactivity
Home > 9-Chloro-17-(2-chloroacetyl)-11,17-dihydroxy-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one furoate > 9-Chloro-17-(2-chloroacetyl)-11,17-dihydroxy-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one furoate(83919-23-7)

9-Chloro-17-(2-chloroacetyl)-11,17-dihydroxy-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one furoate(83919-23-7)

Supplier Product Identification Physical and Chemical Properties First Aid Measures Handling and Storage Exposure Controls/Personal Protection Fire Fighting Measures Accidental Release Measures Stability and Reactivity

Product Identification

Product Name
9-Chloro-17-(2-chloroacetyl)-11,17-dihydroxy-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one furoate
Synonyms
Mometasone 17-(2-furoate)
Pregna-1,4-diene-3,20-dione, 9,21-dichloro-17-((2-furanylcarbonyl)oxy)-11-hydroxy-16-methyl-, (11-beta,16-alpha)
CAS
83919-23-7
Formula
C27H30Cl2O6
Molecular Weight
521.44000000000005
RTECS
TU3822000
Merck
12,6324
Beilstein/Gmelin
4340538

Physical and Chemical Properties

Appearance
Distributed as 0.1% ointment with a petrolatum base.
Solubility in water
Insoluble
Melting Point
218 - 220
Vapor Pressure
4.5E-18 (25 C)
Density
1.37 g/cm3 (20 C)
pKa/pKb
13.05 (pKa)
Partition Coefficient
4.27
Usage
Anti-inflammatory.

First Aid Measures

Ingestion
Give two glasses of water and induce vomiting. Never give anything by mouth to an unconscious person.
Inhalation
Supply fresh air. If required, provide artificial respiration. Keep patient warm. Seek immediate medical advice.
Skin
Wash thoroughly with soap and water.
Eyes
Flush with plenty of water for at least 15 minutes.

Handling and Storage

Storage
Keep container tightly sealed. Store in cool, dry conditions in well sealed containers.

Exposure Controls/Personal Protection

Personal Protection
Protective work clothing. Chemical protective gloves. Safety glasses or goggles.
Exposure Effects
May cause irritation of the eyes and skin. May cause reversible suppression of the Hypothalamic-Pituitary-Adrenal Axis, symptoms of Cushing’s Syndrome, hyperglycemia and glycosuria if ingested.

Fire Fighting Measures

Fire Fighting
Extinguish with carbon dioxide, extinguishing powder or water spray. Fight larger fires with water spray or alcohol resistant foam. Wear self-contained respirator. Wear fully protective impervious suit.

Accidental Release Measures

Small spills/leaks
Assure slippery conditions are nullified. Add sand or dirt. Scoop up and remove, Wash area with soap and water.

Stability and Reactivity

Incompatibilities
Oxidizing agents, bases.
Stability
Stable if stored as directed.
Combustion Products
May emit toxic fumes.
Contact More