Chinese name: Vadira non-hydrochloride
English name: Vardenafil hydrochloride
CAS: 224785-91-5
Molecular formula: C23H33ClN6O4S
Molecular weight: 525.06
category
API: hormone and endocrine function regulating drugs
Melting point: 214-216°C
Storage condition: -20°C
Solubility: DMSO: 100 mg/mL (190.45 mM); Water: ≥ 100 mg/mL (190.45 mM)
Form: solid
Color: White to off-white crystal
InChIKey: XCMULUAPJXCOHI-UHFFFAOYSA-N
SMILES: C (C1 = NC (C) = C2C (N = C (C3C = C (S (N4CCN (CC) CC4) (= O = O) C = CC = 3 occ) NN12) = O) CC. The Cl
intro
Vardenafil hydrochloride is a drug for the treatment of erectile dysfunction in men and is the first line of treatment for erectile dysfunction. Developed by the German Bayer company, it was first marketed in the United States in 2002. Like sildenafil, it is a second generation type 5 phosphodiesterase inhibitor that acts very quickly, taking about 15 to 20 minutes. Ten times more potent than sildenafil. Clinical data show that 50% to 60% of male diabetic patients over 50 years old suffer from erectile dysfunction, and erectile dysfunction caused by nerve and blood vessel damage caused by diabetes is particularly difficult to treat.