| Name | Valsartan |
| Description | Valsartan (CGP 48933) is a tetrazole derivative and angiotensin II type 1 receptor blocker that is used to treat hypertension. |
| In vitro | Valsartan is a potent diuretic, ACE inhibitor, calcium antagonist, and β-blocker.Valsartan dose-dependently inhibited vasoconstriction of angiotensin II-induced vasoconstriction and lowered blood pressure in a renin-dependent model of hypertension. |
| In vivo | Valsartan is a potent diuretic, ACE inhibitor, calcium antagonist, and β-blocker.Valsartan dose-dependently inhibited vasoconstriction of angiotensin II-induced vasoconstriction and lowered blood pressure in a renin-dependent model of hypertension. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | 10% DMSO+90% Corn Oil : 2 mg/mL (4.59 mM), Sonication is recommended. H2O : < 1 mg/mL (insoluble or slightly soluble) DMSO : 250 mg/mL (574.03 mM), Sonication is recommended.
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| Keywords | Valsartan | TLR2 | proinflammatory | pressure | Inhibitor | inhibit | heart | failure | endothelial | cytokines | CGP-48933 | CGP48933 | blood | aorta | Angiotensin Receptor | angiotensin II receptor |
| Inhibitors Related | Losartan potassium | Tranilast | Enalapril Maleate | Telmisartan | Lisinopril dihydrate | Sacubitril/Valsartan | Benzyl benzoate | Irbesartan | Losartan | Ramipril | Diisononyl phthalate | Captopril |
| Related Compound Libraries | Bioactive Compound Library | Pediatric Drug Library | Membrane Protein-targeted Compound Library | EMA Approved Drug Library | Toxic Compound Library | Drug Repurposing Compound Library | Inhibitor Library | FDA-Approved Drug Library | Immunology/Inflammation Compound Library | Bioactive Compounds Library Max | Anti-Metabolism Disease Compound Library | NMPA-Approved Drug Library |