| 名称 | Urotensin I acetate (83930-33-0 Free base) |
| 描述 | Urotensin I acetate, a CRF-like neuropeptide, acts as an agonist of CRF receptor with pEC50s of 11.46, 9.36 and 9.85 for human CRF1, human CRF2 and rat CRF2α receptors in CHO cells, and Kis of 0.4, 1.8, and 5.7 nM for hCRF1, rCRF2α and mCRF2β receptors, respectively[1][2]. |
| 体外活性 | Urotensin I acetate is 2-3 times more potent than CRF or sauvagine in stimulating ACTH release from a superfused goldfish anterior pituitary cell column[3]. Rat tail artery strips were incubated in the presence of 4 x 10(-3) M theophylline and Urotensin I acetate. At the concentrations of 1.50, 7.50 mU/ml but not of 0.75 mU/ml Urotensin I acetate, the content of cAMP increased significantly[4]. |
| 体内活性 | Intraperitoneal injections of urotensin I acetate, a CRF-like neuropeptide isolated from the caudal neurosecretory system of the teleost Catostomus commersoni, ovine CRF and sauvagine all produced significant increases in circulating levels of plasma cortisol in goldfish in which endogenous ACTH secretion was suppressed with betamethasone[3] |
| 存储条件 | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| 关键字 | Urotensin I acetate (83930330 Free base) | Urotensin I acetate (83930 33 0 Free base) | 83930-33-0 Free base | Urotensin I Acetate | 83930-33-0 |
| 相关产品 | Crinecerfont | Tildacerfont | CP 376395 | Antalarmin hydrochloride | Verucerfont | Urocortin, human | CP 316311 | CRF (6-33) acetate(120066-38-8 free base) | Pexacerfont | 4-(2-chloro-4-methoxy-5-methylphenyl)-N-[(1A)-2-cyclopropyl-1-(3-fluoro-4-methylphenyl)ethyl]-5-methyl-N-(2-propyn-1-yl)-2-thiazolamine |
| 相关库 | 多肽分子库 |
United States
