| Description | Urea is a powerful protein denaturant via both direct and indirect mechanisms[1]. A potent emollient and keratolytic agent[2]. Used as a diuretic agent. Blood urea nitrogen (BUN) has been utilized to evaluate renal function[3]. Widely used in fertilizers as a source of nitrogen and is an important raw material for the chemical industry. |
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| Related Catalog | Research Areas >> Cardiovascular Disease Natural Products >> Others |
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| Target | Human Endogenous Metabolite |
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| Solvent | In Vitro: 10 mM in DMSO |
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| Solubility | 1 mM16.6500 mL83.2501 mL166.5002 mL5 mM3.3300 mL16.6500 mL33.3000 mL10 mM1.6650 mL8.3250 mL16.6500 mL |
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| Storage | Powder-20°C3 years 4°C2 yearsIn solvent-80°C6 months -20°C1 month |
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| Shipping | Room temperature in continental US; may vary elsewhere |
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| SMILES | NC(N)=O |
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| References | [1]. Bennion BJ, et al. The molecular basis for the chemical denaturation of proteins by urea. Proc Natl Acad Sci U S A. 2003 Apr 29;100(9):5142-7. [2]. Pan M, et al. Urea: a comprehensive review of the clinical literature. Dermatol Online J. 2013 Nov 15;19(11):20392. [3]. Wang H, et al. Urea. Subcell Biochem. 2014;73:7-29. |
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| Related Molecules | 3-Methyladenine | Hydrocortisone | Acetylcysteine | Tretinoin | Melatonine | Dinoprostone | Nicotinamide | Adenosine triphosphate | 4-Acetamidophenol | Prostaglandin E1 | Dehydroepiandrosterone | Corticosterone | Progesterone | Docosahexaenoic Acid | NAD+ |
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